2021
59. Discovery of a Novel Non-Narcotic Analgesic Derived from the CL-20 Explosive: Synthesis, Pharmacology, and Target Identification of Thiowurtzine, a Potent Inhibitor of the Opioid Receptors and the Ion Channels.
Aguero S, Megy S, Eremina Vv, Kalashnikov Ai, Krylova Sg, Kulagina Da, Lopatina Ka, Fournier M, Povetyeva Tn, Vorozhtsov Ab, Sysolyatin Sv, Zhdanov Vv, Terreux R
(2021) Acs Omega 6 :15400-15411
58. Latent TGF-β Activation Is a Hallmark of the Tenascin Family.
Aubert A, Mercier-gouy P, Aguero S, Berthier L, Liot S, Prigent L, Alcaraz Lb, Verrier B, Terreux R, Moali C, Lambert E, Valcourt U
(2021) Front Immunol 12 :613438-613438
57. Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms.
Da Costa D, Exbrayat-héritier C, Rambaud B, Megy S, Terreux R, Verrier B, Primard C
(2021) J Nanobiotechnology 19 :12-12
56. Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2.
Guragossian N, Belhani B, Moreno A, Nunes Mt, Gonzalez-lobato L, Marminon C, Berthier L, Rocio Andrade Pires Ad, Özvegy-laczka C, Sarkadi B, Terreux R, Bouaziz Z, Berredjem M, Jose J, Di Pietro A, Falson P, Le Borgne M
(2021) Eur J Med Chem 211 :113017-113017
2020
55. Molecular Dynamics Studies of Poly(Lactic Acid) Nanoparticles and Their Interactions with Vitamin E and TLR Agonists Pam1CSK4 and Pam3CSK4.
Megy S, Aguero S, Da Costa D, Lamrayah M, Berthet M, Primard C, Verrier B, Terreux R
(2020) Nanomaterials (basel) 10 :
2019
54. Molecular modelling of TLR agonist Pam(3)CSK(4) entrapment in PLA nanoparticles as a tool to explain loading efficiency and functionality.
Lamrayah M, Charriaud F, Hu S, Megy S, Terreux R, Verrier B
(2019) Int J Pharm 568 :118569-118569
2018
53. In Silico, in Vitro, and in Vivo Evaluation of New Candidates for ?-Synuclein PET Imaging.
Verdurand M, Levigoureux E, Zeinyeh W, Berthier L, Mendjel-herda M, Cadarossanesaib F, Bouillot C, Iecker T, Terreux R, Lancelot S, Chauveau F, Billard T, Zimmer L
(2018) Mol Pharm 15 :3153-3166
2017
52. Ames test prediction on High Energy Molecules by On-The-Fly QSAR (OTF-QSAR)
Alliod C, Chemelle Ja, Jacob G, Terreux R
(2017) Propellants, Explosives, Pyrotechnics 42 :24-35
51. Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.
Bouard C, Terreux R, Tissier A, Jacqueroud L, Vigneron A, Ansieau S, Puisieux A, Payen L
(2017) Bmc Struct Biol 17 :6-6
2016
50. Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences.
Bouard C, Terreux R, Honorat M, Manship B, Ansieau S, Vigneron Am, Puisieux A, Payen L
(2016) Nucleic Acids Res 44 :5470-89
49. Bioinspired Design and Oriented Synthesis of Immunogenic Site-Specifically Penicilloylated Peptides.
Scornet N, Delarue-cochin S, Azoury Me, Le Mignon M, Chemelle Ja, Nony E, Maillere B, Terreux R, Pallardy M, Joseph D
(2016) Bioconjug Chem 27 :2629-2645
48. Unsymmetrical alpha,omega-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis
Zeinyeh W, Radix S, Terreux R, Chemelle Ja, Walchshofer N
(2016) Tetrahedron 72 :4032-4038
2015
47. A Novel Alpha Cardiac Actin (ACTC1) Mutation Mapping to a Domain in Close Contact with Myosin Heavy Chain Leads to a Variety of Congenital Heart Defects, Arrhythmia and Possibly Midline Defects.
Augiere C, Megy S, El Malti R, Boland A, El Zein L, Verrier B, Megarbane A, Deleuze Jf, Bouvagnet P
(2015) Plos One 10 :e0127903-e0127903
46. Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation.
Ballut L, Violot S, Shivakumaraswamy S, Thota Lp, Sathya M, Kunala J, Dijkstra Bw, Terreux R, Haser R, Balaram H, Aghajari N
(2015) Nat Commun 6 :8930-8930
45. A purified truncated form of yeast Gal4 expressed in Escherichia coli and used to functionalize poly(lactic acid) nanoparticle surface is transcriptionally active in cellulo.
Legaz S, Exposito Jy, Borel A, Candusso Mp, Megy S, Montserret R, Lahaye V, Terzian C, Verrier B
(2015) Protein Expr Purif 113 :94-101
44. Quantification and kinetic study in plasma and tissues of (E)-1,1,4,4-tetramethyl-2-tetrazene, a liquid propellant and a transformation product of 1,1-dimethyl hydrazine.
Payen L, Honorat M, Bouard C, Jacob G, Terreux R, Delalu H, Labarthe E, Guitton J
(2015) Anal Bioanal Chem 407 :6721-9
2014
43. Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
Berger C, Romero-brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R
(2014) Gastroenterology 147 :1094-1105
42. Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes.
Bouard C, Terreux R, Hope J, Chemelle Ja, Puisieux A, Ansieau S, Payen L
(2014) J Biomol Struct Dyn 32 :226-41
41. Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux.
Lorendeau D, Dury L, Genoux-bastide E, Lecerf-schmidt F, Simoes-pires C, Carrupt Pa, Terreux R, Magnard S, Di Pietro A, Boumendjel A, Baubichon-cortay H
(2014) Biochem Pharmacol 90 :235-45
40. MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts.
Payen L, Honorat M, Guitton J, Gauthier C, Bouard C, Lecerf-schmidt F, Peres B, Terreux R, Gervot H, Rioufol C, Boumendjel A, Puisieux A, Di Pietro A
(2014) Oncotarget 5 :11957-70
39. Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position.
Winter E, Gozzi Gj, Chiaradia-delatorre Ld, Daflon-yunes N, Terreux R, Gauthier C, Mascarello A, Leal Pc, Cadena Sm, Yunes Ra, Nunes Rj, Creczynski-pasa Tb, Di Pietro A
(2014) Drug Des Devel Ther 8 :609-19
2013
38. Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers.
Dibenedetto S, Cluet D, Stebe Pn, Baumle V, Leault J, Terreux R, Bickle M, Chassey Bd, Mikaelian I, Colas P, Spichty M, Zoli M, Rudkin Bb
(2013) Mol Cell Proteomics 12 :1939-52
37. Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models.
Honorat M, Terreux R, Falson P, Di Pietro A, Dumontet C, Payen L
(2013) Bmc Struct Biol 13 :7-7
36. New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity.
Rangel Lp, Winter E, Gauthier C, Terreux R, Chiaradia-delatorre Ld, Mascarello A, Nunes Rj, Yunes Ra, Creczynski-pasa Tb, Macalou S, Lorendeau D, Baubichon-cortay H, Ferreira-pereira A, Di Pietro A
(2013) Drug Des Devel Ther 7 :1043-52
2012
35. Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
Valdameri G, Gauthier C, Terreux R, Kachadourian R, Day Bj, Winnischofer Sm, Rocha Me, Frachet V, Ronot X, Di Pietro A, Boumendjel A
(2012) J Med Chem 55 :3193-200
34. 6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein.
Valdameri G, Genoux-bastide E, Gauthier C, Peres B, Terreux R, Winnischofer Sm, Rocha Me, Di Pietro A, Boumendjel A
(2012) Chemmedchem 7 :1177-80
33. Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.
Valdameri G, Genoux-bastide E, Peres B, Gauthier C, Guitton J, Terreux R, Winnischofer Sm, Rocha Me, Boumendjel A, Di Pietro A
(2012) J Med Chem 55 :966-70
2011
32. Corticosteroid cross-reactivity: clinical and molecular modelling tools.
Baeck M, Chemelle Ja, Goossens A, Nicolas Jf, Terreux R
(2011) Allergy 66 :1367-74
31. C(16)-methyl corticosteroids are far less allergenic than the non-methylated molecules.
Baeck M, Chemelle Ja, Rasse C, Terreux R, Goossens A
(2011) Contact Dermatitis 64 :305-12
30. Targeting the multidrug ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation.
Boumendjel A, Macalou S, Valdameri G, Pozza A, Gauthier C, Arnaud O, Nicolle E, Magnard S, Falson P, Terreux R, Carrupt Pa, Payen L, Di Pietro A
(2011) Curr Med Chem 18 :3387-401
29. Multidrug resistance ABC transporter structure predictions by homology modeling approaches.
Honorat M, Falson P, Terreux R, Di Pietro A, Dumontet C, Payen L
(2011) Curr Drug Metab 12 :268-77
2010
28. Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export.
Bechet E, Gruszczyk J, Terreux R, Gueguen-chaignon V, Vigouroux A, Obadia B, Cozzone Aj, Nessler S, Grangeasse C
(2010) Mol Microbiol 77 :1315-25
27. Bacterial tyrosine-kinases: structure-function analysis and therapeutic potential.
Grangeasse C, Terreux R, Nessler S
(2010) Biochim Biophys Acta 1804 :628-34
2009
26. Delayed hypersensitivity to corticosteroids in a series of 315 patients: clinical data and patch test results.
Baeck M, Chemelle Ja, Terreux R, Drieghe J, Goossens A
(2009) Contact Dermatitis 61 :163-75
25. The euHCVdb suite of in silico tools for investigating the structural impact of mutations in hepatitis C virus proteins.
Combet C, Bettler E, Terreux R, Garnier N, Deleage G
(2009) Infect Disord Drug Targets 9 :272-8
24. Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment.
Sulka B, Lortat-jacob H, Terreux R, Letourneur F, Rousselle P
(2009) J Biol Chem 284 :10659-71
2006
23. NMR studies for identifying phosphopeptide ligands of the HIV-1 protein Vpu binding to the F-box protein beta-TrCP.
Evrard-todeschi N, Gharbi-benarous J, Bertho G, Coadou G, Megy S, Benarous R, Girault Jp
(2006) Peptides 27 :194-210
22. STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody.
Megy S, Bertho G, Gharbi-benarous J, Baleux F, Benarous R, Girault Jp
(2006) Febs Lett 580 :5411-22
21. Interactions study between the copper II ion and constitutive elements of chitosan structure by DFT calculation.
Terreux R, Domard M, Viton C, Domard A
(2006) Biomacromolecules 7 :31-7
2005
20. A Diels-Alder strategy for the building of imidazo[4,5-g]quinoline-4,9-dione derivatives
Alvarez F, Taleb A, Gentili J, Nebois P, Terreux R, Domard M, Thozet A, Merle D, Fillion H, Walchshofer N
(2005) European Journal Of Organic Chemistry 0 :1903-1908
19. A cyclic PNA-based compound targeting domain IV of HCVIRES RNA inhibits in vitro IRES-dependent translation
Caldarelli Sa, Mehiri M, Di Giorgio A, Martin A, Hantz O, Zoulim F, Terreux R, Condom R, Patino N
(2005) Bioorganic :5700-5709
18. Solution structure of a peptide derived from the oncogenic protein beta-Catenin in its phosphorylated and nonphosphorylated states
Megy S, Bertho G, Gharbi-benarous J, Baleux F, Benarous R, Girault Jp
(2005) Peptides 26 :227-241
17. STD and TRNOESY NMR studies on the conformation of the oncogenic protein beta-catenin containing the phosphorylated motif DpSGXXpS bound to the beta-TrCP protein
Megy S, Bertho G, Gharbi-benarous J, Evrard-todeschi N, Coadou G, Segeral E, Iehle C, Quemeneur E, Benarous R, Girault Jp
(2005) Journal Of Biological Chemistry 280 :29107-29116
16. Synthesis of 6-amino-1H-indole-4,7-quinones
Pringel E, Gentili J, Terreux R, Fenet B, Barret R
(2005) Letters In Organic Chemistry 2 :378-381
15. Isoflavonoids in non-leguminous families: an update
Reynaud J, Guilet D, Terreux R, Lussignol M, Walchshofer N
(2005) Natural Product Reports 22 :504-515
14. Flavonoids and tyrosine nitration: Structure-activity relationship correlation with enthalpy of formation
Sadeghipour M, Terreux R, Phipps J
(2005) Toxicology In Vitro 19 :155-165
13. Antileishmanial activity of polycyclic derivatives.
Sarciron Me, Terreux R, Prieto Y, Cortes M, Cuellar Ma, Tapia Ra, Domard M, Walchshofer N, Petavy Af
(2005) Parasite 12 :251-8
2004
12. Relative antioxidant capacities of propofol and its main metabolites
Boisset S, Steghens Jp, Favetta P, Terreux R, Guitton J
(2004) Archives Of Toxicology 78 :635-642
11. Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR binding
Depecker G, Patino N, Di Giorgio C, Terreux R, Cabrol-bass D, Bailly C, Aubertin Am, Condom R
(2004) Organic :74-79
10. Determination of ddATP levels in human immunodeficiency virus-infected patients treated with dideoxyinosine
Le Saint C, Terreux R, Duval D, Durant J, Ettesse H, Dellamonica P, Guedj R, Vincent Jp, Cupo A
(2004) Antimicrobial Agents And Chemotherapy 48 :589-595
9. Pyrolysis patterns of 5 close Corynebacterium species analyzed by artificial neural networks
Voisin S, Terreux R, Renaud Fnr, Freney J, Domard M, Deruaz D
(2004) Antonie Van Leeuwenhoek International Journal Of General And Molecular Microbiology 85 :287-296
2003
8. NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein beta-TrCP
Coadou G, Gharbi-benarous J, Megy S, Bertho G, Evrard-todeschi N, Segeral E, Benarous R, Girault Jp
(2003) Biochemistry 42 :14741-14751
2002
7. Modelling, synthesis and biological evaluation of an ethidium-arginine conjugate linked to a ribonuclease mimic directed against TAR RNA of HIV-1
Patino N, Di Giorgio C, Dan-covalciuc C, Peytou V, Terreux R, Cabrol-bass D, Bailly C, Condom R
(2002) European Journal Of Medicinal Chemistry 37 :573-584
6. Cyclic PNA hexamer-based compound: modelling, synthesis and inhibition of the HIV-1 RNA dimerization process
Schwergold C, Depecker G, Di Giorgio C, Patino N, Jossinet F, Ehresmann B, Terreux R, Cabrol-bass D, Condom R
(2002) Tetrahedron 58 :5675-5687
2001
5. Amphiphilic anionic analogues of galactosylceramide: synthesis, anti-HIV-1 activity, and gp120 binding.
Faroux-corlay B, Greiner J, Terreux R, Cabrol-bass D, Aubertin Am, Vierling P, Fantini J
(2001) J Med Chem 44 :2188-203
4. Interaction of new PNA-based molecules with TAR RNA of HIV-1: Molecular modelling and biological evaluation
Terreux R, Pairot S, Cabrol-bass D, Patino N, Condom R
(2001) Journal Of Molecular Graphics :579-
2000
3. Dynamic simulation of interaction between HIV-1 RNA loops and PNA cased cyclic molecules.
Terreux R, Antonczak S, Cabrol-bass D, Patino N, Condom R
(2000) Abstracts Of Papers Of The American Chemical Society 220 :U292-U292
1999
2. Synthesis and antiviral activity of ethidium-arginine conjugates directed against the TAR RNA of HIV-1.
Peytou V, Condom R, Patino N, Guedj R, Aubertin Am, Gelus N, Bailly C, Terreux R, Cabrol-bass D
(1999) J Med Chem 42 :4042-53
1. Modeling of the interaction between new ethidium derivatives and TAR RNA of HIV-1
Terreux R, Cabrol-bass D, Peytou V, Condom R, Guedj R
(1999) Journal Of Chemical Information And Computer Sciences 39 :413-419
