Laboratoire de Biologie tissulaire et Ingénierie Thérapeutique – UMR 5305
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Skin Functional Integrity (B. Fromy & J. Lamartine)
Introduction
Axis 1 : Maintaining healthy skin functionality
Axis 2 : Understanding the mechanisms of skin weakening
Axis 3 : Finding indicators of skin weakness
Axis 4 : Therapeutic strategies to recover the functionality of the weakened skin
Expertises
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Cell / microenvironement cross-talk and tissue repair (P. Rousselle)
Introduction
Dialogue cellules / matrice extracellulaire
Members
Publications
Matricellular proteins and pathological deregulations (U. Valcourt)
Introduction
Members
Publications
Metalloproteinases and tissue remodeling (C. Moali)
introduction
Molecular mechanisms of collagen assembly
Role of metalloproteinases and associated regulatory proteins in tissue repair
Development of inhibitors and activators of target proteins
Members
Publications
Osteoarticular and dental research (F. Mallein-Gerin)
Introduction
Biomaterial functionalization for cartilage tissue engineering
Mechanotransduction of chondrocytes
Epigenetics during osteoarthritis
Reconstruction of nasal cartilage using additive fabrication and tissue engineering
Innovative antibacterial hydrogels for dental pulp regeneration
Characteristics of several origins of human stem cells and their capacity to orientate to skeletal lineage
Members
Publications
Colloidal vectors and targeted therapeutic engineering (C. Monge & B. Verrier)
Introduction
Mucosal administration and associated immunity
In vivo uptake of particulate nanovectors and targeted delivery
Particulate nanovaccines and immune responses
NucNanoFish – Nucleic NanoVaccines for Fish – Eranet ICRAD
Bioactive hydrogels and therapeutic biomaterials (Rockefeller, J. Sohier)
Cellular Adaptation and Therapies of Elasticity – ACTE (Rockefeller, R. Debret)
EcMo group (R. Terreux)
Introduction
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Galenic group (Rockefeller, F. Pirot)
Rockefeller pole
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Platforms
LBTI
Histolology and imaging (Primatiss)
Functional explorations of small animal skin tissue (AnexPeau, LBTI)
HPLC detection and quantification platform (Quanti, LBTI)
UMS 3444
Protein Science Facility
PRABI
Education
Presentation
Master Skin biology
Master Bio-imaging
Master Molecular Bioinformatics : methods and analyses
Master Biochemistry
Master Science of drugs and medicines
DU – Prévention et prise en charge des escarres et plaies chroniques apparentées
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Functional Integrity of the Skin
Expertises of the group
