Laboratoire de Biologie tissulaire et Ingénierie Thérapeutique – UMR 5305
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Skin Functional Integrity (B. Fromy & J. Lamartine)
Introduction
Axis 1 : Maintaining healthy skin functionality
Axis 2 : Understanding the mechanisms of skin weakening
Axis 3 : Finding indicators of skin weakness
Axis 4 : Therapeutic strategies to recover the functionality of the weakened skin
Expertises
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Cell / microenvironement cross-talk and tissue repair (P. Rousselle)
Introduction
Dialogue cellules / matrice extracellulaire
Members
Publications
Matricellular proteins and pathological deregulations (U. Valcourt)
Introduction
Members
Metalloproteinases and tissue remodeling (C. Moali)
introduction
Molecular mechanisms of collagen assembly
Role of metalloproteinases and associated regulatory proteins in tissue repair
Development of inhibitors and activators of target proteins
Members
Publications
Osteoarticular and dental research (F. Mallein-Gerin)
Introduction
Identification of signaling pathways triggered by BMP-2 and TGF-beta1
The pathways of mechanotransduction
The signaling pathways under the control of hypoxia, a physiological condition of normal cartilage
Influence of 3D environment and biomaterials on the chondrocyte phenotype
Pathophysiology and regeneration of the pulpodental complex
Characteristics of several origins of human stem cells and their capacity to orientate to skeletal lineage
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Publications
Colloidal vectors and targeted therapeutic engineering (C. Monge & B. Verrier)
Introduction
Elaboration of ecocompatible dual delivery systems
In vivo uptake of particulate nanovectors and targeted delivery
Particulate nanovaccines and immune responses
EcMo group (R. Terreux)
Introduction
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Publications Pôle PRABI
Rockefeller group (…)
Rockefeller pole
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Publications Pôle Rockefeller
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LBTI
Histolology and imaging (Primatiss)
Functional explorations of small animal skin tissue (AnexPeau, LBTI)
UMS 3444
Protein Science Facility
PRABI
Education
Presentation
Master Skin biology
Master Bio-imaging
Master Molecular Bioinformatics : methods and analyses
Master Biochemistry
Master Science of drugs and medicines
DU – Prévention et prise en charge des escarres et plaies chroniques apparentées
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