126 publications trouvées.

126.  BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1. 
Anastasi C, Rousselle P, Talantikite M, Tessier A, Cluzel C, Bachmann A, Mariano N, Dussoyer M, Alcaraz Lb, Fortin L, Aubert A, Delolme F, El Kholti N, Armengaud J, Fournié P, Auxenfans C, Valcourt U, Goff Sv, Moali C
(2020) Sci Signal 13 :  Icon PUBMED

125.  Degradome of soluble ADAM10 and ADAM17 metalloproteases. 
Scharfenberg F, Helbig A, Sammel M, Benzel J, Schlomann U, Peters F, Wichert R, Bettendorff M, Schmidt-arras D, Rose-john S, Moali C, Lichtenthaler Sf, Pietrzik Cu, Bartsch Jw, Tholey A, Becker-pauly C
(2020) Cell Mol Life Sci 77 :331-350  Icon PUBMED

124.  COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing. 
Barnes Am, Ashok A, Makareeva En, Brusel M, Cabral Wa, Weis M, Moali C, Bettler E, Eyre Dr, Cassella Jp, Leikin S, Hulmes Djs, Kessler E, Marini Jc
(2019) Biochim Biophys Acta Mol Basis Dis  :  Icon PUBMED

123.  A scaffold- and serum-free method to mimic human stable cartilage validated by secretome. 
Cortes I, Matsui Ram, Azevedo Ms, Beatrici A, Souza Kla, Launay G, Delolme F, Granjeiro Jm, Moali C, Baptista Ls
(2019) Tissue Eng Part A  :  Icon PUBMED

122.  Atypical COL3A1 variants (glutamic acid to lysine) cause vascular Ehlers-Danlos syndrome with a consistent phenotype of tissue fragility and skin hyperextensibility. 
Ghali N, Baker D, Brady Af, Burrows N, Cervi E, Cilliers D, Frank M, Germain Dp, Hulmes Djs, Jacquemont Ml, Kannu P, Lefroy H, Legrand A, Pope Fm, Robertson L, Vandersteen A, Von Klemperer K, Warburton R, Whiteford M, Van Dijk Fs
(2019) Genet Med  :  Icon PUBMED

121.  C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes. 
Heumuller Se, Talantikite M, Napoli M, Armengaud J, Morgelin M, Hartmann U, Sengle G, Paulsson M, Moali C, Wagener R
(2019) J Biol Chem 294 :13769-13780  Icon PUBMED

120.  Roles of the procollagen C-propeptides in health and disease. 
Hulmes Djs
(2019) Essays Biochem 63 :313-323  Icon PUBMED

119.  Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin. 
Schmelzer Ceh, Heinz A, Troilo H, Lockhart-cairns Mp, Jowitt Ta, Marchand Mf, Bidault L, Bignon M, Hedtke T, Barret A, Mcconnell Jc, Sherratt Mj, Germain S, Hulmes Djs, Baldock C, Muller L
(2019) Faseb J  :fj201801860-fj201801860  Icon PUBMED

118.  Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1. 
Pulido D, Sharma U, Vadon-le Goff S, Hussain Sa, Cordes S, Mariano N, Bettler E, Moali C, Aghajari N, Hohenester E, Hulmes Djs
(2018) Structure  :  Icon PUBMED

117.  Thrombospondin-1 promotes matrix homeostasis by interacting with collagen and lysyl oxidase precursors and collagen cross-linking sites. 
Rosini S, Pugh N, Bonna Am, Hulmes Djs, Farndale Rw, Adams Jc
(2018) Sci Signal 11 :  Icon PUBMED

116.  Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity. 
Talantikite M, Lecorche P, Beau F, Damour O, Becker-pauly C, Ho Wb, Dive V, Vadon-le Goff S, Moali C
(2018) Febs Open Bio 8 :2011-2021  Icon PUBMED

115.  Deficiency of the DSPP-cleaving enzymes meprin ? and meprin ? does not result in dentin malformation in mice. 
Arnold P, Koopmann L, Peters F, Birkenfeld F, Goff Sv, Damm T, Qin C, Moali C, Lucius R, Becker-pauly C
(2017) Cell Tissue Res 367 :351-358  Icon PUBMED

114.  Fibrillar Collagens. 
Bella J, Hulmes Dj
(2017) Subcell Biochem 82 :457-490  Icon PUBMED

113.  Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases. 
Lacroix M, Tessier A, Dumestre-perard C, Vadon-le Goff S, Gout E, Bruckner-tuderman L, Kiritsi D, Nystrom A, Ricard-blum S, Moali C, Hulmes Djs, Thielens Nm
(2017) Sci Rep 7 :16958-16958  Icon PUBMED

112.  Structural basis of homo- and heterotrimerization of collagen I. 
Sharma U, Carrique L, Vadon-le Goff S, Mariano N, Georges Rn, Delolme F, Koivunen P, Myllyharju J, Moali C, Aghajari N, Hulmes Dj
(2017) Nat Commun 8 :14671-14671  Icon PUBMED

111.  Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-? signaling as primary targets. 
Bekhouche M, Leduc C, Dupont L, Janssen L, Delolme F, Vadon-le Goff S, Smargiasso N, Baiwir D, Mazzucchelli G, Zanella-cleon I, Dubail J, De Pauw E, Nusgens B, Hulmes Dj, Moali C, Colige A
(2016) Faseb J 30 :1741-56  Icon PUBMED

110.  Characterization of post-translational modifications in full-length human BMP-1 confirms the presence of a rare vicinal disulfide linkage in the catalytic domain and highlights novel features of the EGF domain. 
Hung Cw, Koudelka T, Anastasi C, Becker A, Moali C, Tholey A
(2016) J Proteomics 138 :136-45  Icon PUBMED

109.  Proteolytic control of TGF-? co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics. 
Delolme F, Anastasi C, Alcaraz Lb, Mendoza V, Vadon-le Goff S, Talantikite M, Capomaccio R, Mevaere J, Fortin L, Mazzocut D, Damour O, Zanella-cleon I, Hulmes Dj, Overall Cm, Valcourt U, Lopez-casillas F, Moali C
(2015) Cell Mol Life Sci 72 :1009-27  Icon PUBMED

108.  Clinical, structural, biochemical and X-ray crystallographic correlates of pathogenicity for variants in the C-propeptide region of the COL3A1 gene. 
Stembridge Ns, Vandersteen Am, Ghali N, Sawle P, Nesbitt M, Pollitt Rc, Ferguson Dj, Holden S, Elmslie F, Henderson A, Hulmes Dj, Pope Fm
(2015) Am J Med Genet A 167A :1763-72  Icon PUBMED

107.  BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling. 
Vadon-le Goff S, Hulmes Dj, Moali C
(2015) Matrix Biol 44-46 :14-23  Icon PUBMED

106.  Upregulation of bone morphogenetic protein-1/mammalian tolloid and procollagen C-proteinase enhancer-1 in corneal scarring. 
Malecaze F, Massoudi D, Fournie P, Tricoire C, Cassagne M, Malbouyres M, Hulmes Dj, Moali C, Galiacy Sd
(2014) Invest Ophthalmol Vis Sci 55 :6712-21  Icon PUBMED

105.  Type I procollagen C-propeptide defects: study of genotype-phenotype correlation and predictive role of crystal structure. 
Symoens S, Hulmes Dj, Bourhis Jm, Coucke Pj, De Paepe A, Malfait F
(2014) Hum Mutat 35 :1330-41  Icon PUBMED

104.  Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation. 
Bourhis Jm, Vadon-le Goff S, Afrache H, Mariano N, Kronenberg D, Thielens N, Moali C, Hulmes Dj
(2013) Proc Natl Acad Sci U S A 110 :6394-9  Icon PUBMED

103.  Metalloproteases meprin ? and meprin ? are C- and N-procollagen proteinases important for collagen assembly and tensile strength. 
Broder C, Arnold P, Vadon-le Goff S, Konerding Ma, Bahr K, Muller S, Overall Cm, Bond Js, Koudelka T, Tholey A, Hulmes Dj, Moali C, Becker-pauly C
(2013) Proc Natl Acad Sci U S A 110 :14219-24  Icon PUBMED

102.  Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases. 
Bijakowski C, Vadon-le Goff S, Delolme F, Bourhis Jm, Lecorche P, Ruggiero F, Becker-pauly C, Yiallouros I, Stocker W, Dive V, Hulmes Dj, Moali C
(2012) J Biol Chem 287 :33581-93  Icon PUBMED

101.  Structural basis of fibrillar collagen trimerization and related genetic disorders. 
Bourhis Jm, Mariano N, Zhao Y, Harlos K, Exposito Jy, Jones Ey, Moali C, Aghajari N, Hulmes Dj
(2012) Nat Struct Mol Biol 19 :1031-6  Icon PUBMED

100.  Production and crystallization of the C-propeptide trimer from human procollagen III. 
Bourhis Jm, Mariano N, Zhao Y, Walter Ts, El Omari K, Delolme F, Moali C, Hulmes Dj, Aghajari N
(2012) Acta Crystallogr Sect F Struct Biol Cryst Commun 68 :1209-13  Icon PUBMED

99.  Development of ex vivo organ culture models to mimic human corneal scarring. 
Janin-manificat H, Rovere Mr, Galiacy Sd, Malecaze F, Hulmes Dj, Moali C, Damour O
(2012) Mol Vis 18 :2896-908  Icon PUBMED

98.  Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only. 
Vadon-le Goff S, Kronenberg D, Bourhis Jm, Bijakowski C, Raynal N, Ruggiero F, Farndale Rw, Stocker W, Hulmes Dj, Moali C
(2011) J Biol Chem 286 :38932-8  Icon PUBMED

97.  Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity. 
Bekhouche M, Kronenberg D, Vadon-le Goff S, Bijakowski C, Lim Nh, Font B, Kessler E, Colige A, Nagase H, Murphy G, Hulmes Dj, Moali C
(2010) J Biol Chem 285 :15950-9  Icon PUBMED

96.  Use of magnetically oriented orthogonal collagen scaffolds for hemi-corneal reconstruction and regeneration. 
Builles N, Janin-manificat H, Malbouyres M, Justin V, Rovere Mr, Pellegrini G, Torbet J, Hulmes Dj, Burillon C, Damour O, Ruggiero F
(2010) Biomaterials 31 :8313-22  Icon PUBMED

95.  Processing of procollagen III by meprins: new players in extracellular matrix assembly? 
Kronenberg D, Bruns Bc, Moali C, Vadon-le Goff S, Sterchi Ee, Traupe H, Bohm M, Hulmes Dj, Stocker W, Becker-pauly C
(2010) J Invest Dermatol 130 :2727-35  Icon PUBMED

94.  Strong cooperativity and loose geometry between CUB domains are the basis for procollagen c-proteinase enhancer activity. 
Kronenberg D, Vadon-le Goff S, Bourhis Jm, Font B, Eichenberger D, Hulmes Dj, Moali C
(2009) J Biol Chem 284 :33437-46  Icon PUBMED

93.  Extracellular and cell surface proteases in wound healing: new players are still emerging. 
Moali C, Hulmes Dj
(2009) Eur J Dermatol 19 :552-64  Icon PUBMED

92.  Procollagen C-proteinase enhancer-1 (POPE-1) interacts with beta 2-microglobulin (beta 2-m) and may help initiate beta 2-m amyloid fibril formation in connective tissues 
Morimoto H , Wada J , Font B , Mott Jd , Hulmes Djs , Ookoshi T , Naiki H , Yasuhara A , Nakatsuka A , Fukuoka K , Takatori Y , Ichikawa H , Akagi S , Nakao K , Makino H
(2008) Matrix Biology 27 :211-219

91.  Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity. 
Blanc G, Font B, Eichenberger D, Moreau C, Ricard-blum S, Hulmes Dj, Moali C
(2007) J Biol Chem 282 :16924-33  Icon PUBMED

90.  Enzymatic cleavage specificity of the proalpha1(V) chain processing analysed by site-directed mutagenesis. 
Bonod-bidaud C, Beraud M, Vaganay E, Delacoux F, Font B, Hulmes Dj, Ruggiero F
(2007) Biochem J 405 :299-306  Icon PUBMED

89.  Development of a hemicornea from human primary cell cultures for pharmacotoxicology testing. 
Builles N, Bechetoille N, Justin V, Andre V, Barbaro V, Di Iorio E, Auxenfans C, Hulmes Dj, Damour O
(2007) Cell Biol Toxicol 23 :279-92  Icon PUBMED

88.  Tissue engineering of the cornea: orthogonal scaffold of magnetically aligned collagen lamellae for corneal stroma reconstruction. 
Torbet J, Malbouyres M, Builles N, Justin V, Roulet M, Damour O, Oldberg A, Ruggiero F, Hulmes Dj
(2007) Conf Proc Ieee Eng Med Biol Soc 2007 :6400-6400  Icon PUBMED

87.  Orthogonal scaffold of magnetically aligned collagen lamellae for corneal stroma reconstruction. 
Torbet J, Malbouyres M, Builles N, Justin V, Roulet M, Damour O, Oldberg A, Ruggiero F, Hulmes Dj
(2007) Biomaterials 28 :4268-76  Icon PUBMED

86.  Inhibition of lysyl oxidase activity can delay phenotypic modulation of chondrocytes in two-dimensional culture. 
Farjanel J, Seve S, Borel A, Sommer P, Hulmes Dj
(2005) Osteoarthritis Cartilage 13 :120-8  Icon PUBMED

85.  Inhibition of lysyl oxidase activity can delay phenotypic modulation of chondrocytes in two-dimensional culture  
Farjanel J, Seve S, Borel A, Sommer P, Hulmes Djs
(2005) International Journal Of Experimental Pathology  86 :A36-A36

84.  Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1. 
Moali C, Font B, Ruggiero F, Eichenberger D, Rousselle P, Francois V, Oldberg A, Bruckner-tuderman L, Hulmes Dj
(2005) J Biol Chem 280 :24188-94  Icon PUBMED

83.  Intra-articular hyaluronate in experimental rabbit osteoarthritis can prevent changes in cartilage proteoglycan content. 
Hulmes Dj, Marsden Me, Strachan Rk, Harvey Re, Mcinnes N, Gardner Dl
(2004) Osteoarthritis Cartilage 12 :232-8  Icon PUBMED

82.  Low resolution structure determination shows procollagen C-proteinase enhancer to be an elongated multidomain glycoprotein. 
Bernocco S, Steiglitz Bm, Svergun Di, Petoukhov Mv, Ruggiero F, Ricard-blum S, Ebel C, Geourjon C, Deleage G, Font B, Eichenberger D, Greenspan Ds, Hulmes Dj
(2003) J Biol Chem 278 :7199-205  Icon PUBMED

81.  Alpha-helical coiled-coil oligomerization domains are almost ubiquitous in the collagen superfamily. 
Mcalinden A, Smith Ta, Sandell Lj, Ficheux D, Parry Da, Hulmes Dj
(2003) J Biol Chem 278 :42200-7  Icon PUBMED

80.  Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis. 
Moali C, Anne C, Lamotte-brasseur J, Groslambert S, Devreese B, Van Beeumen J, Galleni M, Frere Jm
(2003) Chem Biol 10 :319-29  Icon PUBMED

79.  Building collagen molecules, fibrils, and suprafibrillar structures. 
Hulmes Dj
(2002) J Struct Biol 137 :2-10  Icon PUBMED

78.  Interaction properties of the procollagen C-proteinase enhancer protein shed light on the mechanism of stimulation of BMP-1. 
Ricard-blum S, Bernocco S, Font B, Moali C, Eichenberger D, Farjanel J, Burchardt Er, Van Der Rest M, Kessler E, Hulmes Dj
(2002) J Biol Chem 277 :33864-9  Icon PUBMED

77.  Changes in proteoglycan content of articular cartilage during avian degenerative joint disease. 
Anderson-mackenzie Jm, Robins Sp, Thorp Bh, Hulmes Dj
(2001) Clin Exp Rheumatol 19 :159-64  Icon PUBMED

76.  CENTA as a chromogenic substrate for studying beta-lactamases. 
Bebrone C, Moali C, Mahy F, Rival S, Docquier Jd, Rossolini Gm, Fastrez J, Pratt Rf, Frere Jm, Galleni M
(2001) Antimicrob Agents Chemother 45 :1868-71  Icon PUBMED

75.  Biophysical characterization of the C-propeptide trimer from human procollagen III reveals a tri-lobed structure. 
Bernocco S, Finet S, Ebel C, Eichenberger D, Mazzorana M, Farjanel J, Hulmes Dj
(2001) J Biol Chem 276 :48930-6  Icon PUBMED

74.  Lysyl oxidase-like protein from bovine aorta. Isolation and maturation to an active form by bone morphogenetic protein-1. 
Borel A, Eichenberger D, Farjanel J, Kessler E, Gleyzal C, Hulmes Dj, Sommer P, Font B
(2001) J Biol Chem 276 :48944-9  Icon PUBMED

73.  Control of heterotypic fibril formation by collagen V is determined by chain stoichiometry. 
Chanut-delalande H, Fichard A, Bernocco S, Garrone R, Hulmes Dj, Ruggiero F
(2001) J Biol Chem 276 :24352-9  Icon PUBMED

72.  Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity. 
Moali C, Boucher Jl, Renodon-corniere A, Stuehr Dj, Mansuy D
(2001) Chem Res Toxicol 14 :202-10  Icon PUBMED

71.  Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. 
Mollard C, Moali C, Papamicael C, Damblon C, Vessilier S, Amicosante G, Schofield Cj, Galleni M, Frere Jm, Roberts Gc
(2001) J Biol Chem 276 :45015-23  Icon PUBMED

70.  Folding and activity of recombinant human procollagen C-proteinase enhancer. 
Moschcovich L, Bernocco S, Font B, Rivkin H, Eichenberger D, Chejanovsky N, Hulmes Dj, Kessler E
(2001) Eur J Biochem 268 :2991-6  Icon PUBMED

69.  Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes. 
Vadon-le Goff S, Delaforge M, Boucher Jl, Janosik M, Kraus Jp, Mansuy D
(2001) Biochem Biophys Res Commun 283 :487-92  Icon PUBMED

68.  Collagen XI nucleates self-assembly and limits lateral growth of cartilage fibrils. 
Blaschke Uk, Eikenberry Ef, Hulmes Dj, Galla Hj, Bruckner P
(2000) J Biol Chem 275 :10370-8  Icon PUBMED

67.  Liquid crystalline ordering of procollagen as a determinant of three-dimensional extracellular matrix architecture. 
Martin R, Farjanel J, Eichenberger D, Colige A, Kessler E, Hulmes Dj, Giraud-guille Mm
(2000) J Mol Biol 301 :11-7  Icon PUBMED

66.  Large-scale production of procollagen I from chick embryo tendon fibroblasts. 
Martin R, Farjanel J, Eichenberger D, Giraud-guille Mm, Hulmes Dj
(2000) Anal Biochem 277 :276-8  Icon PUBMED

65.  Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity. 
Meurs H, Hamer Ma, Pethe S, Vadon-le Goff S, Boucher Jl, Zaagsma J
(2000) Br J Pharmacol 130 :1793-8  Icon PUBMED

64.  Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. 
Boucher Jl, Moali C, Tenu Jp
(1999) Cell Mol Life Sci 55 :1015-28  Icon PUBMED

63.  Abnormal collagen assembly, though normal phenotype, in alginate bead cultures of chick embryo chondrocytes. 
Gregory Ke, Marsden Me, Anderson-mackenzie J, Bard Jb, Bruckner P, Farjanel J, Robins Sp, Hulmes Dj
(1999) Exp Cell Res 246 :98-107  Icon PUBMED

62.  Articular cartilage proteoglycan metabolism in avian degenerative joint disease: effects of strain selection and body weight. 
Venkatesan N, Thorp Bh, Hulmes Dj
(1999) Connect Tissue Res 40 :199-208  Icon PUBMED

61.  Effects of body mass and genotype on avian degenerative joint disease pathology and articular cartilage proteoglycan distribution. 
Anderson-mackenzie Jm, Hulmes Dj, Thorp Bh
(1998) Clin Exp Rheumatol 16 :403-8  Icon PUBMED

60.  Structural requirements for fibromodulin binding to collagen and the control of type I collagen fibrillogenesis–critical roles for disulphide bonding and the C-terminal region. 
Font B, Eichenberger D, Goldschmidt D, Boutillon Mm, Hulmes Dj
(1998) Eur J Biochem 254 :580-7  Icon PUBMED

59.  Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine. 
Moali C, Boucher Jl, Sari Ma, Stuehr Dj, Mansuy D
(1998) Biochemistry 37 :10453-60  Icon PUBMED

58.  Detection of a nitric oxide synthase possibly involved in the regulation of the Rhodococcus sp R312 nitrile hydratase. 
Sari Ma, Moali C, Boucher Jl, Jaouen M, Mansuy D
(1998) Biochem Biophys Res Commun 250 :364-8  Icon PUBMED

57.  Biosynthesis of NO: mechanism, regulation and control 
Sennequier N, Vadon-le Goff S
(1998) M S-medecine Sciences 14 :1185-1195

56.  Degenerative joint disease in poultry–differences in composition and morphology of articular cartilage are associated with strain susceptibility. 
Anderson-mackenzie Jm, Hulmes Dj, Thorp Bh
(1997) Res Vet Sci 63 :29-33  Icon PUBMED

55.  Highly efficient control of iron-containing nitrile hydratases by stoichiometric amounts of nitric oxide and light. 
Bonnet D, Artaud I, Moali C, Petre D, Mansuy D
(1997) Febs Lett 409 :216-20  Icon PUBMED

54.  N-omega-OH-D,L-indospicine, a potent and selective: Inhibitor of arginase in rat and rabbit alveolar macrophages (AM phi) can promote utilization of L-arginine by nitric oxide synthase (NOS) 
Hey C, Boucher Jl, Vadon S, Ketterer G, Stichnote C, Wessler I, Racke K
(1997) British Journal Of Pharmacology 120 :P48-P48

53.  Inhibition of arginase in rat and rabbit alveolar macrophages by N omega-hydroxy-D,L-indospicine, effects on L-arginine utilization by nitric oxide synthase. 
Hey C, Boucher Jl, Vadon-le Goff S, Ketterer G, Wessler I, Racke K
(1997) Br J Pharmacol 121 :395-400  Icon PUBMED

52.  The CUB domains of procollagen C-proteinase enhancer control collagen assembly solely by their effect on procollagen C-proteinase/bone morphogenetic protein-1. 
Hulmes Dj, Mould Ap, Kessler E
(1997) Matrix Biol 16 :41-5  Icon PUBMED

51.  Expression of active, human lysyl oxidase in E-coli  
Ouzzine M, Boyd A, Hulmes Djs
(1996) Matrix Biology  15 :150-151

50.  Procollagen C-proteinase enhancer is localised to dense connective tissue.  
Robson Aj, Bear Hm, Stewart J, Kessler E, Thorp H, Hulmes Djs
(1996) Matrix Biology  15 :151-151

49.  Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand. 
Sari Ma, Booker S, Jaouen M, Vadon S, Boucher Ji, Pompon D, Mansuy D
(1996) Biochemistry 35 :7204-13  Icon PUBMED

48.  Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of N omega-hydroxyarginine, N omega-hydroxyindospicine and p-hydroxyamidinophenylalanine 
Vadon S, Custot J, Boucher Jl, Mansuy D
(1996) Journal Of The Chemical Society-perkin Transactions 1  :645-648

47.  Radial packing, order, and disorder in collagen fibrils. 
Hulmes Dj, Wess Tj, Prockop Dj, Fratzl P
(1995) Biophys J 68 :1661-70  Icon PUBMED

46.  N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase. 
Boucher Jl, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu Jp, Yapo A, Mansuy D
(1994) Biochem Biophys Res Commun 203 :1614-21  Icon PUBMED

Boucher Jl, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu Jp, Yapo A, Mansuy D
(1994) Biochemical And Biophysical Research Communications 203 :1614-1621

44.  Tyrosine-rich acidic matrix protein (TRAMP) is a tyrosine-sulphated and widely distributed protein of the extracellular matrix. 
Forbes Eg, Cronshaw Ad, Macbeath Jr, Hulmes Dj
(1994) Febs Lett 351 :433-6  Icon PUBMED

43.  Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs. 
Lang Mr, Fiaux Gw, Gillooly M, Stewart Ja, Hulmes Dj, Lamb D
(1994) Thorax 49 :319-26  Icon PUBMED

42.  Heparin binding to monodisperse plasma fibronectin induces aggregation without large-scale changes in conformation in solution. 
Vuillard L, Hulmes Dj, Purdom If, Miller A
(1994) Int J Biol Macromol 16 :21-6  Icon PUBMED

41.  Identification of integrin alpha 2 beta 1 as cell surface receptor for the carboxyl-terminal propeptide of type I procollagen. 
Weston Sa, Hulmes Dj, Mould Ap, Watson Rb, Humphries Mj
(1994) J Biol Chem 269 :20982-6  Icon PUBMED

40.  Chick corneal development in vitro: diverse effects of pH on collagen assembly. 
Bard Jb, Hulmes Dj, Purdom If, Ross As
(1993) J Cell Sci 105 ( Pt 4) :1045-55  Icon PUBMED

39.  Procollagen binding to sphingomyelin. 
Choglay Aa, Purdom If, Hulmes Dj
(1993) J Biol Chem 268 :6107-14  Icon PUBMED

Lang Mr, Fiaux Gw, Gillooly M, Lamb D, Hulmes Djs
(1993) American Review Of Respiratory Disease  147 :A864-A864

37.  Quantitative studies of human lung airspace wall in relation to collagen and elastin content. 
Lang Mr, Fiaux Gw, Hulmes Dj, Lamb D, Miller A
(1993) Matrix 13 :471-80  Icon PUBMED

36.  Tyrosine-rich acidic matrix protein (TRAMP) accelerates collagen fibril formation in vitro. 
Macbeath Jr, Shackleton Dr, Hulmes Dj
(1993) J Biol Chem 268 :19826-32  Icon PUBMED

35.  Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s. 
Renaud Jp, Boucher Jl, Vadon S, Delaforge M, Mansuy D
(1993) Biochem Biophys Res Commun 192 :53-60  Icon PUBMED

34.  Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline. 
Boucher Jl, Genet A, Vadon S, Delaforge M, Henry Y, Mansuy D
(1992) Biochem Biophys Res Commun 187 :880-6  Icon PUBMED

33.  Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins. 
Boucher Jl, Genet A, Vadon S, Delaforge M, Mansuy D
(1992) Biochem Biophys Res Commun 184 :1158-64  Icon PUBMED

32.  On molecular packing in pN-collagen sheets. 
Hulmes Dj
(1992) Int J Biol Macromol 14 :173-4  Icon PUBMED

31.  The collagen superfamily–diverse structures and assemblies. 
Hulmes Dj
(1992) Essays Biochem 27 :49-67  Icon PUBMED

30.  Developmental changes in the type I procollagen processing pathway in chick-embryo cornea. 
Mellor Sj, Atkins Gl, Hulmes Dj
(1991) Biochem J 276 ( Pt 3) :777-84  Icon PUBMED

29.  Assembly of type I collagen fibrils de novo by the specific enzymic cleavage of pC collagen. The fibrils formed at about 37 degrees C are similar in diameter, roundness, and apparent flexibility to the collagen fibrils seen in connective tissue. 
Kadler Ke, Hulmes Dj, Hojima Y, Prockop Dj
(1990) Ann N Y Acad Sci 580 :214-24  Icon PUBMED

28.  Procollagen type I C-proteinase enhancer is a naturally occurring connective tissue glycoprotein. 
Kessler E, Mould Ap, Hulmes Dj
(1990) Biochem Biophys Res Commun 173 :81-6  Icon PUBMED

27.  D-periodic assemblies of type I procollagen. 
Mould Ap, Hulmes Dj, Holmes Df, Cummings C, Sear Ch, Chapman Ja
(1990) J Mol Biol 211 :581-94  Icon PUBMED

26.  Purification of lysyl oxidase from piglet skin by selective interaction with Sephacryl S-200. 
Shackleton Dr, Hulmes Dj
(1990) Biochem J 266 :917-9  Icon PUBMED

25.  Pleomorphism in type I collagen fibrils produced by persistence of the procollagen N-propeptide. 
Hulmes Dj, Kadler Ke, Mould Ap, Hojima Y, Holmes Df, Cummings C, Chapman Ja, Prockop Dj
(1989) J Mol Biol 210 :337-45  Icon PUBMED

24.  Surface-induced aggregation of type I procollagen. 
Mould Ap, Hulmes Dj
(1987) J Mol Biol 195 :543-53  Icon PUBMED

23.  Collagen self-assembly in vitro: electron microscopy of initial aggregates formed during the lag phase. 
Ward Np, Hulmes Dj, Chapman Ja
(1986) J Mol Biol 190 :107-12  Icon PUBMED

22.  Embryonic chick cartilage collagens. Differences in the low-Mr species present in sternal cartilage and tibiotarsal articular cartilage. 
Kielty Cm, Hulmes Dj, Schor Sl, Grant Me
(1984) Febs Lett 169 :179-84  Icon PUBMED

21.  A possible mechanism for the regulation of collagen fibril diameter in vivo. 
Hulmes Dj
(1983) Coll Relat Res 3 :317-21  Icon PUBMED

20.  On the state of aggregation of newly secreted procollagen. 
Hulmes Dj, Bruns Rr, Gross J
(1983) Proc Natl Acad Sci U S A 80 :388-92  Icon PUBMED

Bruns Rr, Hulmes Djs, Gross J
(1982) Journal Of Cell Biology  95 :A130-A130

18.  Electron microscopy shows periodic structure in collagen fibril cross sections. 
Hulmes Dj, Jesior Jc, Miller A, Berthet-colominas C, Wolff C
(1981) Proc Natl Acad Sci U S A 78 :3567-71  Icon PUBMED

17.  Molecular packing in collagen. 
Hulmes Dj, Miller A
(1981) Nature 293 :239-4  Icon PUBMED

Hulmes Djs, Miller A, White Sw, Timmins Pa, Berthetcolominas C
(1980) International Journal Of Biological Macromolecules  2 :338-346

Jesior Jc, Miller A, Hulmes Djs
(1980) Biologie Cellulaire  38 :A12-A12

14.  Procollagen segment-long-spacing crystallites: their role in collagen fibrillogenesis. 
Bruns Rr, Hulmes Dj, Therrien Sf, Gross J
(1979) Proc Natl Acad Sci U S A 76 :313-7  Icon PUBMED

13.  Quasi-hexagonal molecular packing in collagen fibrils. 
Hulmes Dj, Miller A
(1979) Nature 282 :878-80  Icon PUBMED

12.  Structure of collagen in cartilage of intervertebral disk. 
Berthet C, Hulmes Dj, Miller A, Timmins Pa
(1978) Science 199 :547-9  Icon PUBMED

Berthet C, Hulmes Djs, Miller A, Timmins P
(1977) Upsala Journal Of Medical Sciences  82 :121-121

10.  Fundamental periodicities in the amino acid sequence of the collagen alpha1 chain. 
Hulmes Dj, Miller A, Parry Da, Woodhead-galloway J
(1977) Biochem Biophys Res Commun 77 :574-80  Icon PUBMED

9.  Interpretation of the meridional X-ray diffraction pattern from collagen fibres in terms of the known amino acid sequence. 
Hulmes Dj, Miller A, White Sw, Doyle Bb
(1977) J Mol Biol 110 :643-66  Icon PUBMED

8.  Collagen-mineral axial relationship in calcified turkey leg tendon by X-ray and neutron diffraction. 
White Sw, Hulmes Dj, Miller A, Timmins Pa
(1977) Nature 266 :421-5  Icon PUBMED

7.  Letter: Ionic clustering and collagen specificity. 
Doyle Bb, Hukins Dw, Hulmes Dj, Miller A, Rattew Cj, Woodhead-galloway J
(1976) Nature 262 :629-629  Icon PUBMED

6.  Neutron scattering by Collagen. 
Miller A, Doyle Bb, Hulmes Dj, Jenkins Gt, White Jw, Haas J, Ibel K, Timmins P
(1976) Brookhaven Symp Biol 0 :III86-III100  Icon PUBMED

5.  Collagen polymorphism: its origins in the amino acid sequence. 
Doyle Bb, Hukins Dw, Hulmes Dj, Miller A, Woodhead-galloway J
(1975) J Mol Biol 91 :79-99  Icon PUBMED

4.  Origins and implications of the D stagger in collagen. 
Doyle Bb, Hukins Dw, Hulmes Dj, Miller A, Rattew Cj, Woodhead-galloway J
(1974) Biochem Biophys Res Commun 60 :858-64  Icon PUBMED

3.  A D-periodic narrow filament in collagen. 
Doyle Bb, Hulmes Dj, Miller A, Parry Ad, Piez Ka, Woodhead-galloway J
(1974) Proc R Soc Lond B Biol Sci 186 :67-74  Icon PUBMED

2.  Axially projected collagen structures. 
Doyle Bb, Hulmes Dj, Miller A, Parry Da, Piez Ka, Woodhead-galloway J
(1974) Proc R Soc Lond B Biol Sci 187 :37-46  Icon PUBMED

Doyle Bb, Hulmes Djs, Miller A, Parry Dad, Piez Ka, Woodhead.j
(1974) Proceedings Of The Royal Society Of London Series B-biological Sciences  186 :67-