56 publications trouvées.

56.  Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases. 
Vadon-le Goff S, Tessier A, Napoli M, Dieryckx C, Bauer J, Dussoyer M, Lagoutte P, Peyronnel C, Essayan L, Kleiser S, Tueni N, Bettler E, Mariano N, Errazuriz-cerda E, Fruchart Gaillard C, Ruggiero F, Becker-pauly C, Allain Jm, Bruckner-tuderman L, Nyström A, Moali C
(2023) Nat Commun 14 :8020-8020  Icon PUBMED

55.  Comparison of extracellular matrix enrichment protocols for the improved characterization of the skin matrisome by mass spectrometry. 
Dussoyer M, Page A, Delolme F, Rousselle P, Nyström A, Moali C
(2022) J Proteomics 251 :104397-104397  Icon PUBMED

54.  Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1). 
Sharma U, Vadon-le Goff S, Harlos K, Zhao Y, Mariano N, Bijakowski C, Bourhis Jm, Moali C, Hulmes Djs, Aghajari N
(2022) Sci Rep 12 :14850-14850  Icon PUBMED

53.  A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment. 
Alcaraz Lb, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, Boissière-michot F, Simony-lafontaine J, Du Manoir S, Huesgen Pf, Overall Cm, Tartare-deckert S, Jacot W, Chardès T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-coopman E
(2021) Theranostics 11 :6173-6192  Icon PUBMED

52.  Latent TGF-β Activation Is a Hallmark of the Tenascin Family. 
Aubert A, Mercier-gouy P, Aguero S, Berthier L, Liot S, Prigent L, Alcaraz Lb, Verrier B, Terreux R, Moali C, Lambert E, Valcourt U
(2021) Front Immunol 12 :613438-613438  Icon PUBMED

51.  Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity. 
Jeanne A, Sarazin T, Charlé M, Moali C, Fichel C, Boulagnon-rombi C, Callewaert M, Andry Mc, Diesis E, Delolme F, Rioult D, Dedieu S
(2021) Cancers (basel) 13 :  Icon PUBMED

50.  Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis. 
Lagoutte P, Bettler E, Vadon-le Goff S, Moali C
(2021) Matrix Biol Plus 11 :100062-100062  Icon PUBMED

49.  BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1. 
Anastasi C, Rousselle P, Talantikite M, Tessier A, Cluzel C, Bachmann A, Mariano N, Dussoyer M, Alcaraz Lb, Fortin L, Aubert A, Delolme F, El Kholti N, Armengaud J, Fournié P, Auxenfans C, Valcourt U, Goff Sv, Moali C
(2020) Sci Signal 13 :  Icon PUBMED

48.  Degradome of soluble ADAM10 and ADAM17 metalloproteases. 
Scharfenberg F, Helbig A, Sammel M, Benzel J, Schlomann U, Peters F, Wichert R, Bettendorff M, Schmidt-arras D, Rose-john S, Moali C, Lichtenthaler Sf, Pietrzik Cu, Bartsch Jw, Tholey A, Becker-pauly C
(2020) Cell Mol Life Sci 77 :331-350  Icon PUBMED

47.  COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing. 
Barnes Am, Ashok A, Makareeva En, Brusel M, Cabral Wa, Weis M, Moali C, Bettler E, Eyre Dr, Cassella Jp, Leikin S, Hulmes Djs, Kessler E, Marini Jc
(2019) Biochim Biophys Acta Mol Basis Dis  :  Icon PUBMED

46.  A scaffold- and serum-free method to mimic human stable cartilage validated by secretome. 
Cortes I, Matsui Ram, Azevedo Ms, Beatrici A, Souza Kla, Launay G, Delolme F, Granjeiro Jm, Moali C, Baptista Ls
(2019) Tissue Eng Part A  :  Icon PUBMED

45.  C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes. 
Heumuller Se, Talantikite M, Napoli M, Armengaud J, Morgelin M, Hartmann U, Sengle G, Paulsson M, Moali C, Wagener R
(2019) J Biol Chem 294 :13769-13780  Icon PUBMED

44.  Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1. 
Pulido D, Sharma U, Vadon-le Goff S, Hussain Sa, Cordes S, Mariano N, Bettler E, Moali C, Aghajari N, Hohenester E, Hulmes Djs
(2018) Structure  :  Icon PUBMED

43.  Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity. 
Talantikite M, Lecorche P, Beau F, Damour O, Becker-pauly C, Ho Wb, Dive V, Vadon-le Goff S, Moali C
(2018) Febs Open Bio 8 :2011-2021  Icon PUBMED

42.  Deficiency of the DSPP-cleaving enzymes meprin ? and meprin ? does not result in dentin malformation in mice. 
Arnold P, Koopmann L, Peters F, Birkenfeld F, Goff Sv, Damm T, Qin C, Moali C, Lucius R, Becker-pauly C
(2017) Cell Tissue Res 367 :351-358  Icon PUBMED

41.  Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases. 
Lacroix M, Tessier A, Dumestre-perard C, Vadon-le Goff S, Gout E, Bruckner-tuderman L, Kiritsi D, Nystrom A, Ricard-blum S, Moali C, Hulmes Djs, Thielens Nm
(2017) Sci Rep 7 :16958-16958  Icon PUBMED

40.  Structural basis of homo- and heterotrimerization of collagen I. 
Sharma U, Carrique L, Vadon-le Goff S, Mariano N, Georges Rn, Delolme F, Koivunen P, Myllyharju J, Moali C, Aghajari N, Hulmes Dj
(2017) Nat Commun 8 :14671-14671  Icon PUBMED

39.  Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-? signaling as primary targets. 
Bekhouche M, Leduc C, Dupont L, Janssen L, Delolme F, Vadon-le Goff S, Smargiasso N, Baiwir D, Mazzucchelli G, Zanella-cleon I, Dubail J, De Pauw E, Nusgens B, Hulmes Dj, Moali C, Colige A
(2016) Faseb J 30 :1741-56  Icon PUBMED

38.  Characterization of post-translational modifications in full-length human BMP-1 confirms the presence of a rare vicinal disulfide linkage in the catalytic domain and highlights novel features of the EGF domain. 
Hung Cw, Koudelka T, Anastasi C, Becker A, Moali C, Tholey A
(2016) J Proteomics 138 :136-45  Icon PUBMED

37.  Proteolytic control of TGF-? co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics. 
Delolme F, Anastasi C, Alcaraz Lb, Mendoza V, Vadon-le Goff S, Talantikite M, Capomaccio R, Mevaere J, Fortin L, Mazzocut D, Damour O, Zanella-cleon I, Hulmes Dj, Overall Cm, Valcourt U, Lopez-casillas F, Moali C
(2015) Cell Mol Life Sci 72 :1009-27  Icon PUBMED

36.  BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling. 
Vadon-le Goff S, Hulmes Dj, Moali C
(2015) Matrix Biol 44-46 :14-23  Icon PUBMED

35.  Upregulation of bone morphogenetic protein-1/mammalian tolloid and procollagen C-proteinase enhancer-1 in corneal scarring. 
Malecaze F, Massoudi D, Fournie P, Tricoire C, Cassagne M, Malbouyres M, Hulmes Dj, Moali C, Galiacy Sd
(2014) Invest Ophthalmol Vis Sci 55 :6712-21  Icon PUBMED

34.  Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation. 
Bourhis Jm, Vadon-le Goff S, Afrache H, Mariano N, Kronenberg D, Thielens N, Moali C, Hulmes Dj
(2013) Proc Natl Acad Sci U S A 110 :6394-9  Icon PUBMED

33.  Metalloproteases meprin ? and meprin ? are C- and N-procollagen proteinases important for collagen assembly and tensile strength. 
Broder C, Arnold P, Vadon-le Goff S, Konerding Ma, Bahr K, Muller S, Overall Cm, Bond Js, Koudelka T, Tholey A, Hulmes Dj, Moali C, Becker-pauly C
(2013) Proc Natl Acad Sci U S A 110 :14219-24  Icon PUBMED

32.  Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases. 
Bijakowski C, Vadon-le Goff S, Delolme F, Bourhis Jm, Lecorche P, Ruggiero F, Becker-pauly C, Yiallouros I, Stocker W, Dive V, Hulmes Dj, Moali C
(2012) J Biol Chem 287 :33581-93  Icon PUBMED

31.  Structural basis of fibrillar collagen trimerization and related genetic disorders. 
Bourhis Jm, Mariano N, Zhao Y, Harlos K, Exposito Jy, Jones Ey, Moali C, Aghajari N, Hulmes Dj
(2012) Nat Struct Mol Biol 19 :1031-6  Icon PUBMED

30.  Production and crystallization of the C-propeptide trimer from human procollagen III. 
Bourhis Jm, Mariano N, Zhao Y, Walter Ts, El Omari K, Delolme F, Moali C, Hulmes Dj, Aghajari N
(2012) Acta Crystallogr Sect F Struct Biol Cryst Commun 68 :1209-13  Icon PUBMED

29.  Development of ex vivo organ culture models to mimic human corneal scarring. 
Janin-manificat H, Rovere Mr, Galiacy Sd, Malecaze F, Hulmes Dj, Moali C, Damour O
(2012) Mol Vis 18 :2896-908  Icon PUBMED

28.  Procollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only. 
Vadon-le Goff S, Kronenberg D, Bourhis Jm, Bijakowski C, Raynal N, Ruggiero F, Farndale Rw, Stocker W, Hulmes Dj, Moali C
(2011) J Biol Chem 286 :38932-8  Icon PUBMED

27.  Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity. 
Bekhouche M, Kronenberg D, Vadon-le Goff S, Bijakowski C, Lim Nh, Font B, Kessler E, Colige A, Nagase H, Murphy G, Hulmes Dj, Moali C
(2010) J Biol Chem 285 :15950-9  Icon PUBMED

26.  Processing of procollagen III by meprins: new players in extracellular matrix assembly? 
Kronenberg D, Bruns Bc, Moali C, Vadon-le Goff S, Sterchi Ee, Traupe H, Bohm M, Hulmes Dj, Stocker W, Becker-pauly C
(2010) J Invest Dermatol 130 :2727-35  Icon PUBMED

25.  Strong cooperativity and loose geometry between CUB domains are the basis for procollagen c-proteinase enhancer activity. 
Kronenberg D, Vadon-le Goff S, Bourhis Jm, Font B, Eichenberger D, Hulmes Dj, Moali C
(2009) J Biol Chem 284 :33437-46  Icon PUBMED

24.  Extracellular and cell surface proteases in wound healing: new players are still emerging. 
Moali C, Hulmes Dj
(2009) Eur J Dermatol 19 :552-64  Icon PUBMED

23.  Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity. 
Blanc G, Font B, Eichenberger D, Moreau C, Ricard-blum S, Hulmes Dj, Moali C
(2007) J Biol Chem 282 :16924-33  Icon PUBMED

22.  Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1. 
Moali C, Font B, Ruggiero F, Eichenberger D, Rousselle P, Francois V, Oldberg A, Bruckner-tuderman L, Hulmes Dj
(2005) J Biol Chem 280 :24188-94  Icon PUBMED

21.  Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis. 
Moali C, Anne C, Lamotte-brasseur J, Groslambert S, Devreese B, Van Beeumen J, Galleni M, Frere Jm
(2003) Chem Biol 10 :319-29  Icon PUBMED

20.  Interaction properties of the procollagen C-proteinase enhancer protein shed light on the mechanism of stimulation of BMP-1. 
Ricard-blum S, Bernocco S, Font B, Moali C, Eichenberger D, Farjanel J, Burchardt Er, Van Der Rest M, Kessler E, Hulmes Dj
(2002) J Biol Chem 277 :33864-9  Icon PUBMED

19.  CENTA as a chromogenic substrate for studying beta-lactamases. 
Bebrone C, Moali C, Mahy F, Rival S, Docquier Jd, Rossolini Gm, Fastrez J, Pratt Rf, Frere Jm, Galleni M
(2001) Antimicrob Agents Chemother 45 :1868-71  Icon PUBMED

18.  Oxidations of N(omega)-hydroxyarginine analogues and various N-hydroxyguanidines by NO synthase II: key role of tetrahydrobiopterin in the reaction mechanism and substrate selectivity. 
Moali C, Boucher Jl, Renodon-corniere A, Stuehr Dj, Mansuy D
(2001) Chem Res Toxicol 14 :202-10  Icon PUBMED

17.  Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. 
Mollard C, Moali C, Papamicael C, Damblon C, Vessilier S, Amicosante G, Schofield Cj, Galleni M, Frere Jm, Roberts Gc
(2001) J Biol Chem 276 :45015-23  Icon PUBMED

16.  Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes. 
Vadon-le Goff S, Delaforge M, Boucher Jl, Janosik M, Kraus Jp, Mansuy D
(2001) Biochem Biophys Res Commun 283 :487-92  Icon PUBMED

15.  Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity. 
Meurs H, Hamer Ma, Pethe S, Vadon-le Goff S, Boucher Jl, Zaagsma J
(2000) Br J Pharmacol 130 :1793-8  Icon PUBMED

14.  Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization. 
Boucher Jl, Moali C, Tenu Jp
(1999) Cell Mol Life Sci 55 :1015-28  Icon PUBMED

13.  Substrate specificity of NO synthases: detailed comparison of L-arginine, homo-L-arginine, their N omega-hydroxy derivatives, and N omega-hydroxynor-L-arginine. 
Moali C, Boucher Jl, Sari Ma, Stuehr Dj, Mansuy D
(1998) Biochemistry 37 :10453-60  Icon PUBMED

12.  Detection of a nitric oxide synthase possibly involved in the regulation of the Rhodococcus sp R312 nitrile hydratase. 
Sari Ma, Moali C, Boucher Jl, Jaouen M, Mansuy D
(1998) Biochem Biophys Res Commun 250 :364-8  Icon PUBMED

11.  Biosynthesis of NO: mechanism, regulation and control 
Sennequier N, Vadon-le Goff S
(1998) M S-medecine Sciences 14 :1185-1195

10.  Highly efficient control of iron-containing nitrile hydratases by stoichiometric amounts of nitric oxide and light. 
Bonnet D, Artaud I, Moali C, Petre D, Mansuy D
(1997) Febs Lett 409 :216-20  Icon PUBMED

9.  N-omega-OH-D,L-indospicine, a potent and selective: Inhibitor of arginase in rat and rabbit alveolar macrophages (AM phi) can promote utilization of L-arginine by nitric oxide synthase (NOS) 
Hey C, Boucher Jl, Vadon S, Ketterer G, Stichnote C, Wessler I, Racke K
(1997) British Journal Of Pharmacology 120 :P48-P48

8.  Inhibition of arginase in rat and rabbit alveolar macrophages by N omega-hydroxy-D,L-indospicine, effects on L-arginine utilization by nitric oxide synthase. 
Hey C, Boucher Jl, Vadon-le Goff S, Ketterer G, Wessler I, Racke K
(1997) Br J Pharmacol 121 :395-400  Icon PUBMED

7.  Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand. 
Sari Ma, Booker S, Jaouen M, Vadon S, Boucher Ji, Pompon D, Mansuy D
(1996) Biochemistry 35 :7204-13  Icon PUBMED

6.  Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of N omega-hydroxyarginine, N omega-hydroxyindospicine and p-hydroxyamidinophenylalanine 
Vadon S, Custot J, Boucher Jl, Mansuy D
(1996) Journal Of The Chemical Society-perkin Transactions 1  :645-648

5.  N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase. 
Boucher Jl, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu Jp, Yapo A, Mansuy D
(1994) Biochem Biophys Res Commun 203 :1614-21  Icon PUBMED

Boucher Jl, Custot J, Vadon S, Delaforge M, Lepoivre M, Tenu Jp, Yapo A, Mansuy D
(1994) Biochemical And Biophysical Research Communications 203 :1614-1621

3.  Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s. 
Renaud Jp, Boucher Jl, Vadon S, Delaforge M, Mansuy D
(1993) Biochem Biophys Res Commun 192 :53-60  Icon PUBMED

2.  Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline. 
Boucher Jl, Genet A, Vadon S, Delaforge M, Henry Y, Mansuy D
(1992) Biochem Biophys Res Commun 187 :880-6  Icon PUBMED

1.  Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins. 
Boucher Jl, Genet A, Vadon S, Delaforge M, Mansuy D
(1992) Biochem Biophys Res Commun 184 :1158-64  Icon PUBMED