Author Archives: Catherine Moali

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Challenge “Mai à Vélo”: CNRS tops the ranking !

For its first participation in the Challenge Mai à Vélo, the CNRS made a strong impression, finishing on several podiums.

  • The first podium was the employers’ ranking, with CNRS finishing 1st out of 1616 registered employers, with 149,745 km covered.
  • The CNRS DR7, which includes IBCP, LBTI and MMSB, came 1st in the inter-delegation podium, with 22,681 km covered and 131 participants.
  • Finally, the Gerland site ranked 7th out of all national sites, with 3,557 km covered and around twenty participants.

After Mai à vélo, the mobility events continue with the Mobility Challenge on June 4, which attracted around a hundred participants to the IBCP. We’re eagerly awaiting the results!


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LBTI Scientific Day on May 31, 2024

After the memorable 2023 edition at the Clos des Capucins, LBTI members gathered for another day of science and conviviality on May 31 near the Parc de Gerland. The weather wasn’t very cooperative, but there’s no doubt that some great scientific projects have already emerged and will continue to germinate as a result of these exchanges!

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A study from the SKIN group suggest that cells in aged tissues transmit aging messages to neighbouring cells

Communication defects between the cells that make tissues represent a  possible cause of aging. In a study published on November 30, 2024 in the journal Aging, researchers from the SKIN team show that cells from aged skin produce a larger quantity of vesicles, whose molecular content is different from that of vesicles from cells from young skin. These results suggest that some cells in aged tissues may be transmitting a message of aging with a possible remote impact on the behavior of neighboring cells. Link to the publication

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Identification of the endogenous and specific inhibitor of BMP-1/tolloid-like proteinases by the Moali group

BMP-1/tolloid-like proteinases (or BTPs) are critical players during development and tissue repair. While most proteases are regulated by endogenous and specific inhibitors which protect tissues from excessive proteolytic activity, the existence of such an inhibitor in the case of mammalian BTPs has remained elusive. In a study published on December 4th, 2023 in Nature Communications, the Moali group evidenced that the protein known as PCPE-2 is the long-awaited inhibitor of BTPs. This result was very much unexpected as PCPE-2 was previously described as an enhancer of BTP activity.  More detail can be found here

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Patricia Rousselle was awarded the CNRS Innovation Medal : congratulations !

Patricia Rousselle, who is a group leader at LBTI, was recently awarded the CNRS Innovation Medal. Her work is focused on skin wound healing and regeneration and led to the development of several bio-inspired molecules with great pharmaceutical and cosmetic potential. Read more