Author Archives: Catherine Moali

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A meaningful Nobel prize for LBTI !

The Nobel Prize in Physiology and Medicine highlights the importance of temperature and touch receptors. Their groundbreaking discoveries helped understand how heat, cold, and mechanical force can drive the nerve impulses that allow us to perceive and adapt to the world.

The Fromy-Lamartine group is interested in the role of the TRPV3 thermoreceptor in vascular skin thermoregulation in order to specify the transmission of the sensory message via the dialogue between epidermal keratinocytes, sensory nerve endings and dermal microvessels. In this context, they are continuing work to characterize how this signal is altered by aging. =>  Role of the keratinocyte as sensor. Project leaders: B. Fromy & F. Chevalier

This group is also interested in understanding the biological processes that allow healthy skin to resist mechanical stress in order to infer therapeutic approaches to reduce the incidence of pressure ulcers in pathological conditions. => Skin neurovascular alteration and risk of pressure ulcers in paraplegic and diabetic patients. Project leaders: B. Fromy & D. Sigaudo-Roussel