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A new molecular signature to better identify radiosensitive patients

A study co-piloted by researchers from the LGRK (IRCM / CEA-Jacob) and the LBTI (Université Claude Bernard Lyon 1) and carried out on cells from patients who developed severe side effects following radiotherapy, enabled the identification of a new molecular signature of the radiosensitivity of healthy tissues. These results, published in Frontiers in Oncology, show for the first time that NFATC2 gene contributes to the cellular response to ionizing radiation and to radioresistance, paving the way for the study of the mechanisms involved.

More details here: https://jacob.cea.fr/drf/ifrancoisjacob/Pages/Actualites/Actus-scientifiques/2021/nouvelle-signature-moleculaire-identifier-patients-radiosensibles.aspx (French language)