Romain DEBRET
Equipe : Groupe Rockfeller
Courriel : romain.debret@cnrs.fr
Téléphone : +33(0)4-72-72-26-40
Statut : Chargé de recherches
37 publications au total. Seules les 5 dernières années sont affichées
2024
37. The regenerative potential of autologous stem and somatic cells in vitiligo.
Chanteloube S, Debret R
(2024) Eur J Dermatol 34 :13-17
36. A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.
Czarnecka-herok J, Zhu K, Flaman Jm, Goehrig D, Vernier M, Makulyte G, Lamboux A, Dragic H, Rhinn M, Médard Jj, Faury G, Bertolino P, Balter V, Debret R, Adnot S, Martin N, Bernard D
(2024) Redox Biol 73 :103204-103204
2023
35. Dill extract preserves dermal elastic fibers network and functionality. Implication of elafin.
Aimond G, Nicolle S, Debret R, Oréa V, Josset-lamaugarny A, Palierne Jf, Sommer P, Sigaudo-roussel D, Fromy B
(2023) Skin Pharmacol Physiol :
34. Characterization of the Zebrafish Elastin a (elna(sa12235)) Mutant: A New Model of Elastinopathy Leading to Heart Valve Defects.
Hoareau M, El Kholti N, Debret R, Lambert E
(2023) Cells 12 :
2022
33. Physiological Impact of a Synthetic Elastic Protein in Arterial Diseases Related to Alterations of Elastic Fibers: Effect on the Aorta of Elastin-Haploinsufficient Male and Female Mice.
Boëté Q, Lo M, Liu Kl, Vial G, Lemarié E, Rougelot M, Steuckardt I, Harki O, Couturier A, Gaucher J, Bouyon S, Demory A, Boutin-paradis A, El Kholti N, Berthier A, Pépin Jl, Briançon-marjollet A, Lambert E, Debret R, Faury G
(2022) Int J Mol Sci 23 :
32. Design and characterization of an in vivo injectable hydrogel with effervescently generated porosity for regenerative medicine applications.
Griveau L, Lafont M, Le Goff H, Drouglazet C, Robbiani B, Berthier A, Sigaudo-roussel D, Latif N, Visage Cl, Gache V, Debret R, Weiss P, Sohier J
(2022) Acta Biomater 140 :324-337
31. Zebrafish as a Model to Study Vascular Elastic Fibers and Associated Pathologies.
Hoareau M, El Kholti N, Debret R, Lambert E
(2022) Int J Mol Sci 23 :
2019
30. Substrate softness promotes terminal differentiation of human keratinocytes without altering their ability to proliferate back into a rigid environment.
Ya C, Carranca M, Sigaudo-roussel D, Faure P, Fromy B, Debret R
(2019) Arch Dermatol Res 311 :741-751
2018
29. In vitro epidermis model mimicking IGF-1-specific age-related decline.
Mainzer C, Remoue N, Molinari J, Rousselle P, Barricchello C, Lago Jc, Sommer P, Sigaudo-roussel D, Debret R
(2018) Exp Dermatol 27 :537-543
2017
28. Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts.
Moulin L, Cenizo V, Antu An, Andre V, Pain S, Sommer P, Debret R
(2017) Rejuvenation Res 20 :103-110
2016
27. Magnesium Modifies the Structural Features of Enzymatically Mineralized Collagen Gels Affecting the Retraction Capabilities of Human Dermal Fibroblasts Embedded within This 3D System.
Boraldi F, Bartolomeo A, Annovi G, Debret R, Quaglino D
(2016) Materials (basel) 9 :
2015
26. Endothelium microenvironment sensing leading to nitric oxide mediated vasodilation: a review of nervous and biomechanical signals.
Quillon A, Fromy B, Debret R
(2015) Nitric Oxide 45 :20-6
2014
25. Biosynthetic support based on dendritic poly(L-lysine) improves human skin fibroblasts attachment.
Lorion C, Faye C, Maret B, Trimaille T, Regnier T, Sommer P, Debret R
(2014) J Biomater Sci Polym Ed 25 :136-49
24. Insulin-transferrin-selenium as an alternative to foetal serum for epidermal equivalents.
Mainzer C, Barrichello C, Debret R, Remoue N, Sigaudo-roussel D, Sommer P
(2014) Int J Cosmet Sci 36 :427-35
23. [In Process Citation].
Moulin L, Rouvet I, Sommer P, Debret R
(2014) Ann Dermatol Venereol 141 :S94-S94
22. Rheological behaviour of reconstructed skin.
Pailler-mattei C, Laquieze L, Debret R, Tupin S, Aimond G, Sommer P, Zahouani H
(2014) J Mech Behav Biomed Mater 37 :251-63
2013
21. In vivo skin biophysical behaviour and surface topography as a function of ageing.
Pailler-mattei C, Debret R, Vargiolu R, Sommer P, Zahouani H
(2013) J Mech Behav Biomed Mater 28 :474-83
2010
20. Epigenetic silencing of lysyl oxidase-like-1 through DNA hypermethylation in an autosomal recessive cutis laxa case.
Debret R, Cenizo V, Aimond G, Andre V, Devillers M, Rouvet I, Megarbane A, Damour O, Sommer P
(2010) J Invest Dermatol 130 :2594-601
19. Lysyl oxidase silencing impairs keratinocyte differentiation in a reconstructed-epidermis model.
Le Provost Gs, Debret R, Cenizo V, Aimond G, Pez F, Kaniewski B, Andre V, Sommer P
(2010) Exp Dermatol 19 :1080-7
2009
18. Biomechanical devices for skin extracellular matrix disorders: first approach with a cutis laxa patient
Debret R, Pailler-mattei C, Boyer G, Sommer P, Zahouani H
(2009) Journal Of Investigative Dermatology 129 :2527-2527
17. Implication of lysyl oxidase in epidermal homeostasis
Le Provost G, Cenizo V, Debret R, Bouez C, Damour O, Andre V, Sommer P
(2009) Journal Of Investigative Dermatology 129 :795-795
16. lysyl oxidase silencing impairs keratinocyte differentiation
Le Provost G, Debret R, Cenizo V, Kaniewski B, Aimond G, Andre V, Sommer P
(2009) Journal Of Investigative Dermatology 129 :S62-S62
15. Self-etching increases matrix metalloproteinase expression in the dentin-pulp complex.
Lehmann N, Debret R, Romeas A, Magloire H, Degrange M, Bleicher F, Sommer P, Seux D
(2009) J Dent Res 88 :77-82
14. Characterization of the mechanical properties of a dermal equivalent compared with human skin in vivo by indentation and static friction tests.
Zahouani H, Pailler-mattei C, Sohm B, Vargiolu R, Cenizo V, Debret R
(2009) Skin Res Technol 15 :68-76
2008
13. A p.C217R mutation in fibulin-5 from cutis laxa patients is associated with incomplete extracellular matrix formation in a skin equivalent model.
Claus S, Fischer J, Megarbane H, Megarbane A, Jobard F, Debret R, Peyrol S, Saker S, Devillers M, Sommer P, Damour O
(2008) J Invest Dermatol 128 :1442-50
12. Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation.
Debret R, Brassart-pasco S, Lorin J, Martoriati A, Deshorgue A, Maquart Fx, Hornebeck W, Rahman I, Antonicelli F
(2008) Biochim Biophys Acta 1783 :1718-27
2007
11. Elastin receptor (spliced galactosidase) occupancy by elastin peptides counteracts proinflammatory cytokine expression in lipopolysaccharide-stimulated human monocytes through NF-kappaB down-regulation.
Baranek T, Debret R, Antonicelli F, Lamkhioued B, Belaaouaj A, Hornebeck W, Bernard P, Guenounou M, Le Naour R
(2007) J Immunol 179 :6184-92
2006
10. Elastin fragments induce IL-1beta upregulation via NF-kappaB pathway in melanoma cells.
Debret R, Le Naour Rr, Sallenave Jm, Deshorgue A, Hornebeck Wg, Guenounou M, Bernard P, Antonicelli Fd
(2006) J Invest Dermatol 126 :1860-8
2005
9. Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes.
Debret R, Antonicelli F, Theill A, Hornebeck W, Bernard P, Guenounou M, Le Naour R
(2005) Arterioscler Thromb Vasc Biol 25 :1353-8
8. Elastin peptides activate extracellular signal-regulated kinase 1/2 via a Ras-independent mechanism requiring both p110gamma/Raf-1 and protein kinase A/B-Raf signaling in human skin fibroblasts.
Duca L, Lambert E, Debret R, Rothhut B, Blanchevoye C, Delacoux F, Hornebeck W, Martiny L, Debelle L
(2005) Mol Pharmacol 67 :1315-24
2004
7. Elastin-derived peptides up-regulate IL-1 beta expression in melanoma cells
Debret R, Le Naour R, Hornebeck W, Bernard P, Antonicelli F
(2004) Matrix Biology 23 :398-398
6. Elastin-derived peptides induce differential regulation of IL-1 beta and GRO alpha in melanoma cells
Debret R, Le Naour R, Hornebeck W, Bernard P, Antonicelli F
(2004) Journal Of Investigative Dermatology 123 :A105-A105
5. Elastin-derived peptides upregulate IL-1 beta expression in melanoma cells
Debret R, Le Naour R, Hornebeck W, Bernard P, Antonicelli F
(2004) Journal Of Investigative Dermatology 123 :332-
4. ERK1/2 activation by elastin peptides in human skin fibroblasts is Ras-independent and requires both p110 gamma/Raf-1 and PKA/B-Raf signaling pathways
Duca L, Lambert E, Debret R, Rothhut B, Blanchevoye C, Delacoux F, Hornebeck W, Martiny L, Debelle L
(2004) Matrix Biology 23 :399-399
3. Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein.
Ntayi C, Labrousse Al, Debret R, Birembaut P, Bellon G, Antonicelli F, Hornebeck W, Bernard P
(2004) J Invest Dermatol 122 :256-65
2003
2. Annexin A1 processing is associated with caspase-dependent apoptosis in BZR cells.
Debret R, El Btaouri H, Duca L, Rahman I, Radke S, Haye B, Sallenave Jm, Antonicelli F
(2003) Febs Lett 546 :195-202
2002
1. The elastin peptides-mediated induction of pro-collagenase-1 production by human fibroblasts involves activation of MEK/ERK pathway via PKA- and PI(3)K-dependent signaling.
Duca L, Debelle L, Debret R, Antonicelli F, Hornebeck W, Haye B
(2002) Febs Lett 524 :193-8
