Raphael TERREUX
Equipe : Pôle Rhône-alpin de Bio-informatique
Courriel : raphael.terreux@ibcp.fr
Téléphone : +33(0)4-37-65-29-43
Statut : Professeur
2019
47. entrapment in PLA nanoparticles as a tool to explain loading efficiency and functionality.
Lamrayah M, Charriaud F, Hu S, Megy S, Terreux R, Verrier B
(2019) Int J Pharm 568 :118569-118569 
2018
46. In Silico, in Vitro, and in Vivo Evaluation of New Candidates for ?-Synuclein PET Imaging.
Verdurand M, Levigoureux E, Zeinyeh W, Berthier L, Mendjel-herda M, Cadarossanesaib F, Bouillot C, Iecker T, Terreux R, Lancelot S, Chauveau F, Billard T, Zimmer L
(2018) Mol Pharm 15 :3153-3166
2017
45. Ames test prediction on High Energy Molecules by On-The-Fly QSAR (OTF-QSAR)
Alliod C, Chemelle Ja, Jacob G, Terreux R
(2017) Propellants, Explosives, Pyrotechnics 42 :24-35
44. Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.
Bouard C, Terreux R, Tissier A, Jacqueroud L, Vigneron A, Ansieau S, Puisieux A, Payen L
(2017) Bmc Struct Biol 17 :6-6
2016
43. Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences.
Bouard C, Terreux R, Honorat M, Manship B, Ansieau S, Vigneron Am, Puisieux A, Payen L
(2016) Nucleic Acids Res 44 :5470-89
42. Bioinspired Design and Oriented Synthesis of Immunogenic Site-Specifically Penicilloylated Peptides.
Scornet N, Delarue-cochin S, Azoury Me, Le Mignon M, Chemelle Ja, Nony E, Maillere B, Terreux R, Pallardy M, Joseph D
(2016) Bioconjug Chem 27 :2629-2645
41. Unsymmetrical alpha,omega-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis
Zeinyeh W, Radix S, Terreux R, Chemelle Ja, Walchshofer N
(2016) Tetrahedron 72 :4032-4038
2015
40. Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation.
Ballut L, Violot S, Shivakumaraswamy S, Thota Lp, Sathya M, Kunala J, Dijkstra Bw, Terreux R, Haser R, Balaram H, Aghajari N
(2015) Nat Commun 6 :8930-8930
39. Quantification and kinetic study in plasma and tissues of (E)-1,1,4,4-tetramethyl-2-tetrazene, a liquid propellant and a transformation product of 1,1-dimethyl hydrazine.
Payen L, Honorat M, Bouard C, Jacob G, Terreux R, Delalu H, Labarthe E, Guitton J
(2015) Anal Bioanal Chem 407 :6721-9
2014
38. Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
Berger C, Romero-brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R
(2014) Gastroenterology 147 :1094-1105
37. Interhelical loops within the bHLH domain are determinant in maintaining TWIST1-DNA complexes.
Bouard C, Terreux R, Hope J, Chemelle Ja, Puisieux A, Ansieau S, Payen L
(2014) J Biomol Struct Dyn 32 :226-41
36. Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux.
Lorendeau D, Dury L, Genoux-bastide E, Lecerf-schmidt F, Simoes-pires C, Carrupt Pa, Terreux R, Magnard S, Di Pietro A, Boumendjel A, Baubichon-cortay H
(2014) Biochem Pharmacol 90 :235-45
35. MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts.
Payen L, Honorat M, Guitton J, Gauthier C, Bouard C, Lecerf-schmidt F, Peres B, Terreux R, Gervot H, Rioufol C, Boumendjel A, Puisieux A, Di Pietro A
(2014) Oncotarget 5 :11957-70
34. Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position.
Winter E, Gozzi Gj, Chiaradia-delatorre Ld, Daflon-yunes N, Terreux R, Gauthier C, Mascarello A, Leal Pc, Cadena Sm, Yunes Ra, Nunes Rj, Creczynski-pasa Tb, Di Pietro A
(2014) Drug Des Devel Ther 8 :609-19
2013
33. Calcineurin A versus NS5A-TP2/HD domain containing 2: a case study of site-directed low-frequency random mutagenesis for dissecting target specificity of peptide aptamers.
Dibenedetto S, Cluet D, Stebe Pn, Baumle V, Leault J, Terreux R, Bickle M, Chassey Bd, Mikaelian I, Colas P, Spichty M, Zoli M, Rudkin Bb
(2013) Mol Cell Proteomics 12 :1939-52
32. Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2′-deoxyuridine-5′-monophosphate on ABCC11 in silico models.
Honorat M, Terreux R, Falson P, Di Pietro A, Dumontet C, Payen L
(2013) Bmc Struct Biol 13 :7-7
31. New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity.
Rangel Lp, Winter E, Gauthier C, Terreux R, Chiaradia-delatorre Ld, Mascarello A, Nunes Rj, Yunes Ra, Creczynski-pasa Tb, Macalou S, Lorendeau D, Baubichon-cortay H, Ferreira-pereira A, Di Pietro A
(2013) Drug Des Devel Ther 7 :1043-52
2012
30. Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
Valdameri G, Gauthier C, Terreux R, Kachadourian R, Day Bj, Winnischofer Sm, Rocha Me, Frachet V, Ronot X, Di Pietro A, Boumendjel A
(2012) J Med Chem 55 :3193-200
29. 6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein.
Valdameri G, Genoux-bastide E, Gauthier C, Peres B, Terreux R, Winnischofer Sm, Rocha Me, Di Pietro A, Boumendjel A
(2012) Chemmedchem 7 :1177-80
28. Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.
Valdameri G, Genoux-bastide E, Peres B, Gauthier C, Guitton J, Terreux R, Winnischofer Sm, Rocha Me, Boumendjel A, Di Pietro A
(2012) J Med Chem 55 :966-70
2011
27. Corticosteroid cross-reactivity: clinical and molecular modelling tools.
Baeck M, Chemelle Ja, Goossens A, Nicolas Jf, Terreux R
(2011) Allergy 66 :1367-74
26. C(16)-methyl corticosteroids are far less allergenic than the non-methylated molecules.
Baeck M, Chemelle Ja, Rasse C, Terreux R, Goossens A
(2011) Contact Dermatitis 64 :305-12
25. Targeting the multidrug ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation.
Boumendjel A, Macalou S, Valdameri G, Pozza A, Gauthier C, Arnaud O, Nicolle E, Magnard S, Falson P, Terreux R, Carrupt Pa, Payen L, Di Pietro A
(2011) Curr Med Chem 18 :3387-401
24. Multidrug resistance ABC transporter structure predictions by homology modeling approaches.
Honorat M, Falson P, Terreux R, Di Pietro A, Dumontet C, Payen L
(2011) Curr Drug Metab 12 :268-77
2010
23. Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export.
Bechet E, Gruszczyk J, Terreux R, Gueguen-chaignon V, Vigouroux A, Obadia B, Cozzone Aj, Nessler S, Grangeasse C
(2010) Mol Microbiol 77 :1315-25
22. Bacterial tyrosine-kinases: structure-function analysis and therapeutic potential.
Grangeasse C, Terreux R, Nessler S
(2010) Biochim Biophys Acta 1804 :628-34
2009
21. Delayed hypersensitivity to corticosteroids in a series of 315 patients: clinical data and patch test results.
Baeck M, Chemelle Ja, Terreux R, Drieghe J, Goossens A
(2009) Contact Dermatitis 61 :163-75
20. The euHCVdb suite of in silico tools for investigating the structural impact of mutations in hepatitis C virus proteins.
Combet C, Bettler E, Terreux R, Garnier N, Deleage G
(2009) Infect Disord Drug Targets 9 :272-8
19. Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment.
Sulka B, Lortat-jacob H, Terreux R, Letourneur F, Rousselle P
(2009) J Biol Chem 284 :10659-71
2006
18. Interactions study between the copper II ion and constitutive elements of chitosan structure by DFT calculation.
Terreux R, Domard M, Viton C, Domard A
(2006) Biomacromolecules 7 :31-7
2005
17. A Diels-Alder strategy for the building of imidazo[4,5-g]quinoline-4,9-dione derivatives
Alvarez F, Taleb A, Gentili J, Nebois P, Terreux R, Domard M, Thozet A, Merle D, Fillion H, Walchshofer N
(2005) European Journal Of Organic Chemistry 0 :1903-1908
16. A cyclic PNA-based compound targeting domain IV of HCVIRES RNA inhibits in vitro IRES-dependent translation
Caldarelli Sa, Mehiri M, Di Giorgio A, Martin A, Hantz O, Zoulim F, Terreux R, Condom R, Patino N
(2005) Bioorganic :5700-5709
15. Synthesis of 6-amino-1H-indole-4,7-quinones
Pringel E, Gentili J, Terreux R, Fenet B, Barret R
(2005) Letters In Organic Chemistry 2 :378-381
14. Isoflavonoids in non-leguminous families: an update
Reynaud J, Guilet D, Terreux R, Lussignol M, Walchshofer N
(2005) Natural Product Reports 22 :504-515
13. Flavonoids and tyrosine nitration: Structure-activity relationship correlation with enthalpy of formation
Sadeghipour M, Terreux R, Phipps J
(2005) Toxicology In Vitro 19 :155-165
12. Antileishmanial activity of polycyclic derivatives.
Sarciron Me, Terreux R, Prieto Y, Cortes M, Cuellar Ma, Tapia Ra, Domard M, Walchshofer N, Petavy Af
(2005) Parasite 12 :251-8
2004
11. Relative antioxidant capacities of propofol and its main metabolites
Boisset S, Steghens Jp, Favetta P, Terreux R, Guitton J
(2004) Archives Of Toxicology 78 :635-642
10. Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR binding
Depecker G, Patino N, Di Giorgio C, Terreux R, Cabrol-bass D, Bailly C, Aubertin Am, Condom R
(2004) Organic :74-79
9. Determination of ddATP levels in human immunodeficiency virus-infected patients treated with dideoxyinosine
Le Saint C, Terreux R, Duval D, Durant J, Ettesse H, Dellamonica P, Guedj R, Vincent Jp, Cupo A
(2004) Antimicrobial Agents And Chemotherapy 48 :589-595
8. Pyrolysis patterns of 5 close Corynebacterium species analyzed by artificial neural networks
Voisin S, Terreux R, Renaud Fnr, Freney J, Domard M, Deruaz D
(2004) Antonie Van Leeuwenhoek International Journal Of General And Molecular Microbiology 85 :287-296
2002
7. Modelling, synthesis and biological evaluation of an ethidium-arginine conjugate linked to a ribonuclease mimic directed against TAR RNA of HIV-1
Patino N, Di Giorgio C, Dan-covalciuc C, Peytou V, Terreux R, Cabrol-bass D, Bailly C, Condom R
(2002) European Journal Of Medicinal Chemistry 37 :573-584
6. Cyclic PNA hexamer-based compound: modelling, synthesis and inhibition of the HIV-1 RNA dimerization process
Schwergold C, Depecker G, Di Giorgio C, Patino N, Jossinet F, Ehresmann B, Terreux R, Cabrol-bass D, Condom R
(2002) Tetrahedron 58 :5675-5687
2001
5. Amphiphilic anionic analogues of galactosylceramide: synthesis, anti-HIV-1 activity, and gp120 binding.
Faroux-corlay B, Greiner J, Terreux R, Cabrol-bass D, Aubertin Am, Vierling P, Fantini J
(2001) J Med Chem 44 :2188-203
4. Interaction of new PNA-based molecules with TAR RNA of HIV-1: Molecular modelling and biological evaluation
Terreux R, Pairot S, Cabrol-bass D, Patino N, Condom R
(2001) Journal Of Molecular Graphics :579-
2000
3. Dynamic simulation of interaction between HIV-1 RNA loops and PNA cased cyclic molecules.
Terreux R, Antonczak S, Cabrol-bass D, Patino N, Condom R
(2000) Abstracts Of Papers Of The American Chemical Society 220 :U292-U292
1999
2. Synthesis and antiviral activity of ethidium-arginine conjugates directed against the TAR RNA of HIV-1.
Peytou V, Condom R, Patino N, Guedj R, Aubertin Am, Gelus N, Bailly C, Terreux R, Cabrol-bass D
(1999) J Med Chem 42 :4042-53
1. Modeling of the interaction between new ethidium derivatives and TAR RNA of HIV-1
Terreux R, Cabrol-bass D, Peytou V, Condom R, Guedj R
(1999) Journal Of Chemical Information And Computer Sciences 39 :413-419
