Mini Curriculum Vitae

Nicolas PICARD

Equipe : Fonctionnalité et dynamique du tissu cutané
Courriel :
Téléphone : +33(0)4-37-65-29-34
Statut : Chargé de recherches

54.  TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. 
Arhatte M, Gunaratne Gs, El Boustany C, Kuo Iy, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-gervais S, Ehrlich Be, Marchant Js, Savage Am, Van Eeden Fjm, Wilkinson Rn, Demolombe S, Honore E, Patel A
(2019) Nat Commun 10 :2024-2024  Icon PUBMED

53.  Editorial. 
Becquemont L, Picard N, Verstuyft C
(2017) Therapie 72 :173-174  Icon PUBMED

Becquemont L, Picard N, Verstuyft C
(2017) Therapie 72 :171-172  Icon PUBMED

51.  Cutaneous and renal vasodilatory response to local pressure application: A comparative study in mice. 
Begey Al, Liu Kl, Lo M, Josset-lamaugarny A, Picard N, Gauthier C, Fromy B, Sigaudo-roussel D, Dubourg L
(2017) Microvasc Res 115 :44-51  Icon PUBMED

50.  Towards therapeutic drug monitoring of everolimus in cancer? Results of an exploratory study of exposure-effect relationship. 
Deppenweiler M, Falkowski S, Saint-marcoux F, Monchaud C, Picard N, Laroche Ml, Tubiana-mathieu N, Venat-bouvet L, Marquet P, Woillard Jb
(2017) Pharmacol Res 121 :138-144  Icon PUBMED

49.  Characterization and identification of eight designer benzodiazepine metabolites by incubation with human liver microsomes and analysis by a triple quadrupole mass spectrometer. 
El Balkhi S, Chaslot M, Picard N, Dulaurent S, Delage M, Mathieu O, Saint-marcoux F
(2017) Int J Legal Med 131 :979-988  Icon PUBMED

48.  The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron. 
Hennings Jc, Andrini O, Picard N, Paulais M, Huebner Ak, Cayuqueo Ik, Bignon Y, Keck M, Corniere N, Bohm D, Jentsch Tj, Chambrey R, Teulon J, Hubner Ca, Eladari D
(2017) J Am Soc Nephrol 28 :209-217  Icon PUBMED

47.  Intercalated Cell Depletion and Vacuolar H(+)-ATPase Mistargeting in an Ae1 R607H Knockin Model. 
Mumtaz R, Trepiccione F, Hennings Jc, Huebner Ak, Serbin B, Picard N, Ullah Akms, P?unescu Tg, Capen De, Lashhab Rm, Mouro-chanteloup I, Alper Sl, Wagner Ca, Cordat E, Brown D, Eladari D, Hubner Ca
(2017) J Am Soc Nephrol 28 :1507-1520  Icon PUBMED

46.  Pharmacogenetics-based personalized therapy: Levels of evidence and recommendations from the French Network of Pharmacogenetics (RNPGx). 
Picard N, Boyer Jc, Etienne-grimaldi Mc, Barin-le Guellec C, Thomas F, Loriot Ma,
(2017) Therapie 72 :185-192  Icon PUBMED

Picard N, Boyer Jc, Etienne-grimaldi Mc, Barin-le Guellec C, Thomas F, Loriot Ma,
(2017) Therapie 72 :175-183  Icon PUBMED

44.  Pharmacogenetics of immunosuppressants: State of the art and clinical implementation – recommendations from the French National Network of Pharmacogenetics (RNPGx). 
Woillard Jb, Chouchana L, Picard N, Loriot Ma,
(2017) Therapie 72 :285-299  Icon PUBMED

Woillard Jb, Chouchana L, Picard N, Loriot Ma,
(2017) Therapie 72 :269-284  Icon PUBMED

42.  Plasma and intracellular exposure to ganciclovir in adult renal transplant recipients: is there an association with haematological toxicity? 
Billat Pa, Woillard Jb, Essig M, Sauvage Fl, Picard N, Alain S, Neely M, Marquet P, Saint-marcoux F
(2016) J Antimicrob Chemother 71 :484-9  Icon PUBMED

41.  Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation. 
Brunet M, Shipkova M, Van Gelder T, Wieland E, Sommerer C, Budde K, Haufroid V, Christians U, Lopez-hoyos M, Barten Mj, Bergan S, Picard N, Millan Lopez O, Marquet P, Hesselink Da, Noceti O, Pawinski T, Wallemacq P, Oellerich M
(2016) Ther Drug Monit 38 Suppl 1 :S1-20  Icon PUBMED

40.  Influence of Donor and Recipient CYP3A4, CYP3A5, and ABCB1 Genotypes on Clinical Outcomes and Nephrotoxicity in Liver Transplant Recipients. 
Debette-gratien M, Woillard Jb, Picard N, Sebagh M, Loustaud-ratti V, Sautereau D, Samuel D, Marquet P
(2016) Transplantation 100 :2129-2137  Icon PUBMED

39.  Positive biodiversity-productivity relationship predominant in global forests. 
Liang J, Crowther Tw, Picard N, Wiser S, Zhou M, Alberti G, Schulze Ed, Mcguire Ad, Bozzato F, Pretzsch H, De-miguel S, Paquette A, Herault B, Scherer-lorenzen M, Barrett Cb, Glick Hb, Hengeveld Gm, Nabuurs Gj, Pfautsch S, Viana H, Vibrans Ac, Ammer C, Schall P, Verbyla D, Tchebakova N, Fischer M, Watson Jv, Chen Hy, Lei X, Schelhaas Mj, Lu H, Gianelle D, Parfenova Ei, Salas C, Lee E, Lee B, Kim Hs, Bruelheide H, Coomes Da, Piotto D, Sunderland T, Schmid B, Gourlet-fleury S, Sonke B, Tavani R, Zhu J, Brandl S, Vayreda J, Kitahara F, Searle Eb, Neldner Vj, Ngugi Mr, Baraloto C, Frizzera L, Ba?azy R, Oleksyn J, Zawi?a-nied?wiecki T, Bouriaud O, Bussotti F, Finer L, Jaroszewicz B, Jucker T, Valladares F, Jagodzinski Am, Peri Pl, Gonmadje C, Marthy W, O’brien T, Martin Eh, Marshall Ar, Rovero F, Bitariho R, Niklaus Pa, Alvarez-loayza P, Chamuya N, Valencia R, Mortier F, Wortel V, Engone-obiang Nl, Ferreira Lv, Odeke De, Vasquez Rm, Lewis Sl, Reich Pb
(2016) Science 354 :  Icon PUBMED

38.  Efficiency and Safety of an Early Dose Adjustment of Ribavirin in Patients Infected With Hepatitis C Underexposed to the Drug and Treated With Peginterferon Ribavirin. 
Loustaud-ratti V, Maynard M, Thevenon S, Pradat P, Rousseau A, Alain S, Deny P, Gagnieu Mc, Tran A, Dao T, Silvain C, Lunel-fabiani F, Picard N, Zublena I, Marquet P, Trepo C,
(2016) Ther Drug Monit 38 :684-692  Icon PUBMED

37.  Piezo1-dependent regulation of urinary osmolarity. 
Martins Jr, Penton D, Peyronnet R, Arhatte M, Moro C, Picard N, Kurt B, Patel A, Honore E, Demolombe S
(2016) Pflugers Arch 468 :1197-206  Icon PUBMED

36.  Inactivation of the Dorsal Premotor Area Disrupts Internally Generated, But Not Visually Guided, Sequential Movements. 
Ohbayashi M, Picard N, Strick Pl
(2016) J Neurosci 36 :1971-6  Icon PUBMED

35.  Chronic Administration of the N-Methyl-D-Aspartate Receptor Antagonist Ketamine Improves Rett Syndrome Phenotype. 
Patrizi A, Picard N, Simon Aj, Gunner G, Centofante E, Andrews Na, Fagiolini M
(2016) Biol Psychiatry 79 :755-64  Icon PUBMED

34.  Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs. 
Picard N, Bergan S, Marquet P, Van Gelder T, Wallemacq P, Hesselink Da, Haufroid V
(2016) Ther Drug Monit 38 Suppl 1 :S57-69  Icon PUBMED

33.  A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes in renal transplantation. 
Pouche L, Koitka M, Stojanova J, Woillard Jb, Monchaud C, Villeneuve C, Essig M, Abraham J, Le Meur Y, Rerolle Jp, Kamar N, Rostaing L, Merville P, Gandia P, Bouchet S, Petersen Bs, Marquet P, Picard N
(2016) Pharmacogenomics 17 :375-91  Icon PUBMED

32.  New challenges and promises in solid organ transplantation pharmacogenetics: the genetic variability of proteins involved in the pharmacodynamics of immunosuppressive drugs. 
Pouche L, Stojanova J, Marquet P, Picard N
(2016) Pharmacogenomics 17 :277-96  Icon PUBMED

31.  Therapeutic Drug Monitoring of Everolimus: A Consensus Report. 
Shipkova M, Hesselink Da, Holt Dw, Billaud Em, Van Gelder T, Kunicki Pk, Brunet M, Budde K, Barten Mj, De Simone P, Wieland E, Lopez Om, Masuda S, Seger C, Picard N, Oellerich M, Langman Lj, Wallemacq P, Morris Rg, Thompson C, Marquet P
(2016) Ther Drug Monit 38 :143-69  Icon PUBMED

30.  Analytical Aspects of the Implementation of Biomarkers in Clinical Transplantation. 
Shipkova M, Lopez Om, Picard N, Noceti O, Sommerer C, Christians U, Wieland E
(2016) Ther Drug Monit 38 Suppl 1 :S80-92  Icon PUBMED

29.  Genetic polymorphisms in the immune response: A focus on kidney transplantation. 
Stojanova J, Pouche L, Picard N
(2016) Clin Biochem 49 :363-76  Icon PUBMED

28.  Cortical Feedback Regulates Feedforward Retinogeniculate Refinement. 
Thompson Ad, Picard N, Min L, Fagiolini M, Chen C
(2016) Neuron 91 :1021-1033  Icon PUBMED

27.  Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System. 
Trepiccione F, Gerber Sd, Grahammer F, Lopez-cayuqueo Ki, Baudrie V, P?unescu Tg, Capen De, Picard N, Alexander Rt, Huber Tb, Chambrey R, Brown D, Houillier P, Eladari D, Simons M
(2016) J Am Soc Nephrol 27 :3320-3330  Icon PUBMED

26.  Does Epoetin Beta Still Have a Place in Peginterferon Alpha-2a Plus Ribavirin Treatment Strategies for Chronic Hepatitis C? 
Veillon P, Fouchard-hubert I, Larrey D, Dao Mt, D’alteroche L, Boyer-darrigand N, Picard N, Le Guillou-guillemette H, Saulnier P, Ducancelle A, Loustaud-ratti V, Lunel-fabiani F
(2016) J Interferon Cytokine Res 36 :204-14  Icon PUBMED

25.  SDF1 induction by acidosis from principal cells regulates intercalated cell subtype distribution. 
Schwartz Gj, Gao X, Tsuruoka S, Purkerson Jm, Peng H, D’agati V, Picard N, Eladari D, Al-awqati Q
(2015) J Clin Invest 125 :4365-74  Icon PUBMED

24.  Mechanisms of renal control of potassium homeostasis in complete aldosterone deficiency. 
Todkar A, Picard N, Loffing-cueni D, Sorensen Mv, Mihailova M, Nesterov V, Makhanova N, Korbmacher C, Wagner Ca, Loffing J
(2015) J Am Soc Nephrol 26 :425-38  Icon PUBMED

23.  Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation. 
Eladari D, Chambrey R, Picard N, Hadchouel J
(2014) Cell Mol Life Sci 71 :2879-95  Icon PUBMED

22.  Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension. 
Picard N, Trompf K, Yang Cl, Miller Rl, Carrel M, Loffing-cueni D, Fenton Ra, Ellison Dh, Loffing J
(2014) J Am Soc Nephrol 25 :511-22  Icon PUBMED

21.  The absence of intrarenal ACE protects against hypertension. 
Gonzalez-villalobos Ra, Janjoulia T, Fletcher Nk, Giani Jf, Nguyen Mt, Riquier-brison Ad, Seth Dm, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-peterdi J, Navar Lg, Bernstein Ke, Mcdonough Aa
(2013) J Clin Invest 123 :2011-23  Icon PUBMED

20.  Overexpression of pendrin in intercalated cells produces chloride-sensitive hypertension. 
Jacques T, Picard N, Miller Rl, Riemondy Ka, Houillier P, Sohet F, Ramakrishnan Sk, Busst Cj, Jayat M, Corniere N, Hassan H, Aronson Ps, Hennings Jc, Hubner Ca, Nelson Rd, Chambrey R, Eladari D
(2013) J Am Soc Nephrol 24 :1104-13  Icon PUBMED

19.  SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice. 
Li X, Sanneman Jd, Harbidge Dg, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith Aj, Marcus Dc, Wangemann P
(2013) Plos Genet 9 :e1003641-e1003641  Icon PUBMED

18.  A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. 
Hennings Jc, Picard N, Huebner Ak, Stauber T, Maier H, Brown D, Jentsch Tj, Vargas-poussou R, Eladari D, Hubner Ca
(2012) Embo Mol Med 4 :1057-71  Icon PUBMED

17.  Role of tissue kallikrein in regulation of tubule function. 
Chambrey R, Picard N
(2011) Curr Opin Nephrol Hypertens 20 :523-8  Icon PUBMED

16.  Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome. 
Paulais M, Bloch-faure M, Picard N, Jacques T, Ramakrishnan Sk, Keck M, Sohet F, Eladari D, Houillier P, Lourdel S, Teulon J, Tucker Sj
(2011) Proc Natl Acad Sci U S A 108 :10361-6  Icon PUBMED

15.  Tissue kallikrein permits early renal adaptation to potassium load. 
El Moghrabi S, Houillier P, Picard N, Sohet F, Wootla B, Bloch-faure M, Leviel F, Cheval L, Frische S, Meneton P, Eladari D, Chambrey R
(2010) Proc Natl Acad Sci U S A 107 :13526-31  Icon PUBMED

14.  Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. 
Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R, Glick Ab, Hahnel B, Hosser H, Grone Hj, Kriz W
(2010) Am J Pathol 177 :632-43  Icon PUBMED

13.  Acute parathyroid hormone differentially regulates renal brush border membrane phosphate cotransporters. 
Picard N, Capuano P, Stange G, Mihailova M, Kaissling B, Murer H, Biber J, Wagner Ca
(2010) Pflugers Arch 460 :677-87  Icon PUBMED

12.  Tissue kallikrein deficiency and renovascular hypertension in the mouse. 
Griol-charhbili V, Sabbah L, Colucci J, Vincent Mp, Baudrie V, Laude D, Elghozi Jl, Bruneval P, Picard N, Meneton P, Alhenc-gelas F, Richer C
(2009) Am J Physiol Regul Integr Comp Physiol 296 :R1385-91  Icon PUBMED

11.  Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption. 
Nowik M, Picard N, Stange G, Capuano P, Tenenhouse Hs, Biber J, Murer H, Wagner Ca
(2008) Pflugers Arch 457 :539-49  Icon PUBMED

10.  Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. 
Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M
(2008) Histochem Cell Biol 130 :141-55  Icon PUBMED

9.  Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney. 
Pizard A, Richer C, Bouby N, Picard N, Meneton P, Azizi M, Alhenc-gelas F
(2008) Biol Chem 389 :701-6  Icon PUBMED

8.  Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells. 
Vogetseder A, Picard N, Gaspert A, Walch M, Kaissling B, Le Hir M
(2008) Am J Physiol Cell Physiol 294 :C22-8  Icon PUBMED

7.  Immunolocalization of phospho-S6 kinases: a new way to detect mitosis in tissue sections and in cell culture. 
Schmidt T, Wahl P, Wuthrich Rp, Vogetseder A, Picard N, Kaissling B, Le Hir M
(2007) Histochem Cell Biol 127 :123-9  Icon PUBMED

6.  Mice chronically fed a westernized experimental diet as a model of obesity, metabolic syndrome and osteoporosis. 
Demigne C, Bloch-faure M, Picard N, Sabboh H, Besson C, Remesy C, Geoffroy V, Gaston At, Nicoletti A, Hagege A, Menard J, Meneton P
(2006) Eur J Nutr 45 :298-306  Icon PUBMED

5.  Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5. 
Gkika D, Topala Cn, Chang Q, Picard N, Thebault S, Houillier P, Hoenderop Jg, Bindels Rj
(2006) Embo J 25 :4707-16  Icon PUBMED

4.  Pendrin regulation in mouse kidney primarily is chloride-dependent. 
Vallet M, Picard N, Loffing-cueni D, Fysekidis M, Bloch-faure M, Deschenes G, Breton S, Meneton P, Loffing J, Aronson Ps, Chambrey R, Eladari D
(2006) J Am Soc Nephrol 17 :2153-63  Icon PUBMED

3.  Genetic ablation of Rhbg in the mouse does not impair renal ammonium excretion. 
Chambrey R, Goossens D, Bourgeois S, Picard N, Bloch-faure M, Leviel F, Geoffroy V, Cambillau M, Colin Y, Paillard M, Houillier P, Cartron Jp, Eladari D
(2005) Am J Physiol Renal Physiol 289 :F1281-90  Icon PUBMED

2.  Tissue kallikrein-deficient mice display a defect in renal tubular calcium absorption. 
Picard N, Van Abel M, Campone C, Seiler M, Bloch-faure M, Hoenderop Jg, Loffing J, Meneton P, Bindels Rj, Paillard M, Alhenc-gelas F, Houillier P
(2005) J Am Soc Nephrol 16 :3602-10  Icon PUBMED

1.  Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels. 
Gogelein H, Brendel J, Steinmeyer K, Strubing C, Picard N, Rampe D, Kopp K, Busch Ae, Bleich M
(2004) Naunyn Schmiedebergs Arch Pharmacol 370 :183-92  Icon PUBMED