Mini Curriculum Vitae

MOALI Catherine
Catherine MOALI

Ingénieure Chimiste ESPCI-ParisTech (1995)
Diplômée de l’Institut de Formation Supérieure Biomédicale (IFSBM, Université Paris Sud, 1998)
Doctorat de l’Université Paris Sud (1999)
HDR de l’Université Claude Bernard Lyon I (2011)


Précédents laboratoires :

- Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Paris (1994-1999)
- Centre d’Ingénierie des Protéines, Liège (1999-2001)
- Institut de Biologie et Chimie des Protéines, Lyon (2001-2010)


Responsable de l’Equipe Métalloprotéases et Remodelage Tissulaire
Directrice adjointe de la SFR Biosciences (http://www.sfr-biosciences.fr/)

Mots-clés : Métalloprotéases, Matrice Extracellulaire, TGF-?, Cicatrisation, Fibroses, Protéomique, Interactions Protéines-Protéines

Equipe : Métalloprotéases et Remodelage tissulaire
Courriel : catherine.moali@ibcp.fr
Téléphone : +33(0)4-72-72-26-38
Statut : Directeur de recherches

42 publications au total. Seules les 5 dernières années sont affichées

2022
42.  Comparison of extracellular matrix enrichment protocols for the improved characterization of the skin matrisome by mass spectrometry. 
Dussoyer M, Page A, Delolme F, Rousselle P, Nyström A, Moali C
(2022) J Proteomics 251 :104397-104397  Icon PUBMED

2021
41.  A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment. 
Alcaraz Lb, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, Boissière-michot F, Simony-lafontaine J, Du Manoir S, Huesgen Pf, Overall Cm, Tartare-deckert S, Jacot W, Chardès T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-coopman E
(2021) Theranostics 11 :6173-6192  Icon PUBMED

40.  Latent TGF-β Activation Is a Hallmark of the Tenascin Family. 
Aubert A, Mercier-gouy P, Aguero S, Berthier L, Liot S, Prigent L, Alcaraz Lb, Verrier B, Terreux R, Moali C, Lambert E, Valcourt U
(2021) Front Immunol 12 :613438-613438  Icon PUBMED

39.  Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity. 
Jeanne A, Sarazin T, Charlé M, Moali C, Fichel C, Boulagnon-rombi C, Callewaert M, Andry Mc, Diesis E, Delolme F, Rioult D, Dedieu S
(2021) Cancers (basel) 13 :  Icon PUBMED

38.  Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis. 
Lagoutte P, Bettler E, Vadon-le Goff S, Moali C
(2021) Matrix Biol Plus 11 :100062-100062  Icon PUBMED

2020
37.  BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1. 
Anastasi C, Rousselle P, Talantikite M, Tessier A, Cluzel C, Bachmann A, Mariano N, Dussoyer M, Alcaraz Lb, Fortin L, Aubert A, Delolme F, El Kholti N, Armengaud J, Fournié P, Auxenfans C, Valcourt U, Goff Sv, Moali C
(2020) Sci Signal 13 :  Icon PUBMED

36.  Degradome of soluble ADAM10 and ADAM17 metalloproteases. 
Scharfenberg F, Helbig A, Sammel M, Benzel J, Schlomann U, Peters F, Wichert R, Bettendorff M, Schmidt-arras D, Rose-john S, Moali C, Lichtenthaler Sf, Pietrzik Cu, Bartsch Jw, Tholey A, Becker-pauly C
(2020) Cell Mol Life Sci 77 :331-350  Icon PUBMED

2019
35.  COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing. 
Barnes Am, Ashok A, Makareeva En, Brusel M, Cabral Wa, Weis M, Moali C, Bettler E, Eyre Dr, Cassella Jp, Leikin S, Hulmes Djs, Kessler E, Marini Jc
(2019) Biochim Biophys Acta Mol Basis Dis  :  Icon PUBMED

34.  A scaffold- and serum-free method to mimic human stable cartilage validated by secretome. 
Cortes I, Matsui Ram, Azevedo Ms, Beatrici A, Souza Kla, Launay G, Delolme F, Granjeiro Jm, Moali C, Baptista Ls
(2019) Tissue Eng Part A  :  Icon PUBMED

33.  C-terminal proteolysis of the collagen VI α3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes. 
Heumuller Se, Talantikite M, Napoli M, Armengaud J, Morgelin M, Hartmann U, Sengle G, Paulsson M, Moali C, Wagener R
(2019) J Biol Chem 294 :13769-13780  Icon PUBMED

2018
32.  Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1. 
Pulido D, Sharma U, Vadon-le Goff S, Hussain Sa, Cordes S, Mariano N, Bettler E, Moali C, Aghajari N, Hohenester E, Hulmes Djs
(2018) Structure  :  Icon PUBMED

31.  Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity. 
Talantikite M, Lecorche P, Beau F, Damour O, Becker-pauly C, Ho Wb, Dive V, Vadon-le Goff S, Moali C
(2018) Febs Open Bio 8 :2011-2021  Icon PUBMED

2017
30.  Deficiency of the DSPP-cleaving enzymes meprin ? and meprin ? does not result in dentin malformation in mice. 
Arnold P, Koopmann L, Peters F, Birkenfeld F, Goff Sv, Damm T, Qin C, Moali C, Lucius R, Becker-pauly C
(2017) Cell Tissue Res 367 :351-358  Icon PUBMED

29.  Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases. 
Lacroix M, Tessier A, Dumestre-perard C, Vadon-le Goff S, Gout E, Bruckner-tuderman L, Kiritsi D, Nystrom A, Ricard-blum S, Moali C, Hulmes Djs, Thielens Nm
(2017) Sci Rep 7 :16958-16958  Icon PUBMED

28.  Structural basis of homo- and heterotrimerization of collagen I. 
Sharma U, Carrique L, Vadon-le Goff S, Mariano N, Georges Rn, Delolme F, Koivunen P, Myllyharju J, Moali C, Aghajari N, Hulmes Dj
(2017) Nat Commun 8 :14671-14671  Icon PUBMED