Jean-Yves EXPOSITO
Equipe : Vecteurs colloïdaux et ingénierie thérapeutique ciblée
Courriel : jean-yves.exposito@ibcp.fr
Téléphone : +33(0)4-72-72-26-90
Statut : Chargé de recherches
47 publications au total. Seules les 5 dernières années sont affichées
2023
47. Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes.
Marlétaz F, Couloux A, Poulain J, Labadie K, Da Silva C, Mangenot S, Noel B, Poustka Aj, Dru P, Pegueroles C, Borra M, Lowe Ek, Lhomond G, Besnardeau L, Le Gras S, Ye T, Gavriouchkina D, Russo R, Costa C, Zito F, Anello L, Nicosia A, Ragusa Ma, Pascual M, Molina Md, Chessel A, Di Carlo M, Turon X, Copley Rr, Exposito Jy, Martinez P, Cavalieri V, Ben Tabou De Leon S, Croce J, Oliveri P, Matranga V, Di Bernardo M, Morales J, Cormier P, Geneviève Am, Aury Jm, Barbe V, Wincker P, Arnone Mi, Gache C, Lepage T
(2023) Cell Genom 3 :100295-100295
46. DLin-MC3-Containing mRNA Lipid Nanoparticles Induce an Antibody Th2-Biased Immune Response Polarization in a Delivery Route-Dependent Manner in Mice.
Yavuz A, Coiffier C, Garapon C, Gurcan S, Monge C, Exposito Jy, Arruda Dc, Verrier B
(2023) Pharmaceutics 15 :
2022
45. Comparison of Physicochemical Properties of LipoParticles as mRNA Carrier Prepared by Automated Microfluidic System and Bulk Method.
Ayad C, Yavuz A, Salvi Jp, Libeau P, Exposito Jy, Ginet V, Monge C, Verrier B, Arruda Dc
(2022) Pharmaceutics 14 :
2021
44. Combining an optimized mRNA template with a double purification process allows strong expression of in vitro transcribed mRNA.
Linares-fernández S, Moreno J, Lambert E, Mercier-gouy P, Vachez L, Verrier B, Exposito Jy
(2021) Mol Ther Nucleic Acids 26 :945-956
2019
43. Poly(lactic acid) nanoparticles and cell-penetrating peptide potentiate mRNA-based vaccine expression in dendritic cells triggering their activation.
Coolen Al, Lacroix C, Mercier-gouy P, Delaune E, Monge C, Exposito Jy, Verrier B
(2019) Biomaterials 195 :23-37
42. Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response.
Linares-fernandez S, Lacroix C, Exposito Jy, Verrier B
(2019) Trends Mol Med :
2016
41. Poly(Lactic Acid) Nanoparticles Targeting ?5?1 Integrin as Vaccine Delivery Vehicle, a Prospective Study.
Dalzon B, Lebas C, Jimenez G, Gutjahr A, Terrat C, Exposito Jy, Verrier B, Lethias C
(2016) Plos One 11 :e0167663-e0167663
40. Evaluation of polylactic acid nanoparticles safety using Drosophila model.
Legaz S, Exposito Jy, Lethias C, Viginier B, Terzian C, Verrier B
(2016) Nanotoxicology 10 :1136-43
2015
39. A purified truncated form of yeast Gal4 expressed in Escherichia coli and used to functionalize poly(lactic acid) nanoparticle surface is transcriptionally active in cellulo.
Legaz S, Exposito Jy, Borel A, Candusso Mp, Megy S, Montserret R, Lahaye V, Terzian C, Verrier B
(2015) Protein Expr Purif 113 :94-101
38. Tenascin-X: beyond the architectural function.
Valcourt U, Alcaraz Lb, Exposito Jy, Lethias C, Bartholin L
(2015) Cell Adh Migr 9 :154-65
2014
37. Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β.
Alcaraz Lb, Exposito Jy, Chuvin N, Pommier Rm, Cluzel C, Martel S, Sentis S, Bartholin L, Lethias C, Valcourt U
(2014) J Cell Biol 205 :409-28
2012
36. Structural basis of fibrillar collagen trimerization and related genetic disorders.
Bourhis Jm, Mariano N, Zhao Y, Harlos K, Exposito Jy, Jones Ey, Moali C, Aghajari N, Hulmes Dj
(2012) Nat Struct Mol Biol 19 :1031-6
2011
35. Isolation, characterization and biological evaluation of jellyfish collagen for use in biomedical applications.
Addad S, Exposito Jy, Faye C, Ricard-blum S, Lethias C
(2011) Mar Drugs 9 :967-83
2010
34. The fibrillar collagen family.
Exposito Jy, Valcourt U, Cluzel C, Lethias C
(2010) Int J Mol Sci 11 :407-26
33. Tenascin-X increases the stiffness of collagen gels without affecting fibrillogenesis.
Margaron Y, Bostan L, Exposito Jy, Malbouyres M, Trunfio-sfarghiu Am, Berthier Y, Lethias C
(2010) Biophys Chem 147 :87-91
2008
32. Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human.
Exposito Jy, Larroux C, Cluzel C, Valcourt U, Lethias C, Degnan Bm
(2008) J Biol Chem 283 :28226-35
2006
31. Insights into early extracellular matrix evolution: spongin short chain collagen-related proteins are homologous to basement membrane type IV collagens and form a novel family widely distributed in invertebrates.
Aouacheria A, Geourjon C, Aghajari N, Navratil V, Deleage G, Lethias C, Exposito Jy
(2006) Mol Biol Evol 23 :2288-302
30. A model of tenascin-X integration within the collagenous network.
Lethias C, Carisey A, Comte J, Cluzel C, Exposito Jy
(2006) Febs Lett 580 :6281-5
2004
29. Invertebrate data predict an early emergence of vertebrate fibrillar collagen clades and an anti-incest model.
Aouacheria A, Cluzel C, Lethias C, Gouy M, Garrone R, Exposito Jy
(2004) J Biol Chem 279 :47711-9
28. Distinct maturations of N-propeptide domains in fibrillar procollagen molecules involved in the formation of heterotypic fibrils in adult sea urchin collagenous tissues.
Cluzel C, Lethias C, Garrone R, Exposito Jy
(2004) J Biol Chem 279 :9811-7
2002
27. Evolution of collagens.
Exposito Jy, Cluzel C, Garrone R, Lethias C
(2002) Anat Rec 268 :302-16
2001
26. Characterization of fibrosurfin, an interfibrillar component of sea urchin catch connective tissues.
Cluzel C, Lethias C, Humbert F, Garrone R, Exposito Jy
(2001) J Biol Chem 276 :18108-14
25. Binding of tenascin-X to decorin.
Elefteriou F, Exposito Jy, Garrone R, Lethias C
(2001) Febs Lett 495 :44-7
24. Identification and characterization of a conformational heparin-binding site involving two fibronectin type III modules of bovine tenascin-X.
Lethias C, Elefteriou F, Parsiegla G, Exposito Jy, Garrone R
(2001) J Biol Chem 276 :16432-8
2000
23. Sea urchin fibrillar collagen 2alpha chain participates in heterotrimeric molecules of (1alpha)(2)2alpha stoichiometry.
Cluzel C, Lethias C, Garrone R, Exposito Jy
(2000) Matrix Biol 19 :545-7
22. Production in mammalian cells of chimeric human/sea urchin procollagen molecules displaying distinct versions of the minor triple helix.
Cluzel C, Lethias C, Garrone R, Exposito Jy
(2000) J Biochem 128 :957-63
21. Tracing the evolution of vertebrate fibrillar collagens from an ancestral alpha chain.
Exposito J, Cluzel C, Lethias C, Garrone R
(2000) Matrix Biol 19 :275-9
20. Triple helix assembly and processing of human collagen produced in transgenic tobacco plants.
Ruggiero F, Exposito Jy, Bournat P, Gruber V, Perret S, Comte J, Olagnier B, Garrone R, Theisen M
(2000) Febs Lett 469 :132-6
19. Molecular adaptation to an extreme environment: origin of the thermal stability of the pompeii worm collagen.
Sicot Fx, Mesnage M, Masselot M, Exposito Jy, Garrone R, Deutsch J, Gaill F
(2000) J Mol Biol 302 :811-20
1999
18. Cell adhesion to tenascin-X mapping of cell adhesion sites and identification of integrin receptors.
Elefteriou F, Exposito Jy, Garrone R, Lethias C
(1999) Eur J Biochem 263 :840-8
1997
17. Characterization of the bovine tenascin-X.
Elefteriou F, Exposito Jy, Garrone R, Lethias C
(1997) J Biol Chem 272 :22866-74
16. Collagen fibrillogenesis during sea urchin development--retention of SURF motifs from the N-propeptide of the 2alpha chain in mature fibrils.
Lethias C, Exposito Jy, Garrone R
(1997) Eur J Biochem 245 :434-40
15. Cloning of an annelid fibrillar-collagen gene and phylogenetic analysis of vertebrate and invertebrate collagens.
Sicot Fx, Exposito Jy, Masselot M, Garrone R, Deutsch J, Gaill F
(1997) Eur J Biochem 246 :50-8
14. Comparative analysis of fibrillar and basement membrane collagen expression in embryos of the sea urchin, Strongylocentrotus purpuratus.
Suzuki Hr, Reiter Rs, D'alessio M, Di Liberto M, Ramirez F, Exposito Jy, Gambino R, Solursh M
(1997) Zoolog Sci 14 :449-54
1996
13. Type IV collagen in sponges, the missing link in basement membrane ubiquity.
Boute N, Exposito Jy, Boury-esnault N, Vacelet J, Noro N, Miyazaki K, Yoshizato K, Garrone R
(1996) Biol Cell 88 :37-44
1995
12. Characterization of two genes coding for a similar four-cysteine motif of the amino-terminal propeptide of a sea urchin fibrillar collagen.
Exposito Jy, Boute N, Deleage G, Garrone R
(1995) Eur J Biochem 234 :59-65
1994
11. Identification of a cell lineage-specific gene coding for a sea urchin alpha 2(IV)-like collagen chain.
Exposito Jy, Suzuki H, Geourjon C, Garrone R, Solursh M, Ramirez F
(1994) J Biol Chem 269 :13167-71
1993
10. Complete primary structure of a sea urchin type IV collagen alpha chain and analysis of the 5' end of its gene.
Exposito Jy, D'alessio M, Di Liberto M, Ramirez F
(1993) J Biol Chem 268 :5249-54
9. The complete intron/exon structure of Ephydatia mulleri fibrillar collagen gene suggests a mechanism for the evolution of an ancestral gene module.
Exposito Jy, Van Der Rest M, Garrone R
(1993) J Mol Evol 37 :254-9
8. [Phylogenesis of the extracellular matrix].
Garrone R, Exposito Jy, Franc Jm, Franc S, Humbert-david N, Qin L, Tillet E
(1993) C R Seances Soc Biol Fil 187 :114-23
1992
7. Novel amino-terminal propeptide configuration in a fibrillar procollagen undergoing alternative splicing.
Exposito Jy, D'alessio M, Ramirez F
(1992) J Biol Chem 267 :17404-8
6. Sea urchin collagen evolutionarily homologous to vertebrate pro-alpha 2(I) collagen.
Exposito Jy, D'alessio M, Solursh M, Ramirez F
(1992) J Biol Chem 267 :15559-62
5. THE COLLAGEN FAMILY OF PROTEINS - 2 DISTINCT LINES OF EVOLUTION
Garrone R, Exposito Jy
(1992) Belgian Journal Of Zoology 122 :17-22
1991
4. Short chain collagens in sponges are encoded by a family of closely related genes.
Exposito Jy, Le Guellec D, Lu Q, Garrone R
(1991) J Biol Chem 266 :21923-8
1990
3. Characterization of a fibrillar collagen gene in sponges reveals the early evolutionary appearance of two collagen gene families.
Exposito Jy, Garrone R
(1990) Proc Natl Acad Sci U S A 87 :6669-73
2. Cloning and sequencing of a Porifera partial cDNA coding for a short-chain collagen.
Exposito Jy, Ouazana R, Garrone R
(1990) Eur J Biochem 190 :401-6
1. A MINIATURE COLLAGEN DISCOVERED IN SPONGES BY CDNA CLONING
Exposito Jy, Vincent P, Garrone R
(1990) Annals Of The New York Academy Of Sciences 580 :444-447